Evidence map›Paper›PMID 42062016›Full record

ReviewPhysical medicine and rehabilitation clinics of North America2026

Relationship Between Spinal Reflexes and Spastic Movement Disorders.

Aiko K Thompson, Thomas Sinkjær

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Physical medicine and rehabilitation clinics of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aiko K ThompsonDepartment of Health Sciences and Research, College of Health Professions, Medical University of South Carolina, Charleston, SC, USA. Electronic address: thompsai@musc.edu.
Thomas SinkjærDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.

Funding

Spinal Reflex Conditioning System for Enhancing Motor Function Recovery After Incomplete Spinal Cord InjuryU44NS114420 · NINDS · BIOCIRCUIT TECHNOLOGIES, INC. · PI Isaac Perry Clements, Aiko Thompson · 2020 to 2026
$5.1M
Characterization of Physiological Changes Induced Through MEP Conditioning in People with SCIR01NS114279 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI THOMPSON, AIKO · 2020 to 2024
$1.6M
NINDS NIH HHS R01 NS114279NINDS NIH HHS U44 NS114420
6 · The paper itself

Abstract

The central nervous system (CNS) generates various motor functions, in part by modulating the excitability of spinal reflex pathways. When a reflex becomes not modulable or its modulation becomes impaired due to spinal cord lesions or other CNS diseases, it could become a part of spastic movement disorders. For the CNS with or without chronic lesions, thus, reflexes can be used as tools to probe its state. Utilizing such features of spinal reflexes, it is possible to operantly condition a reflex to improve CNS activity and resulting motor function in spastic individuals with spinal cord lesions.

Indexed as

Movement DisordersMuscle SpasticityReflexReflex, StretchSpinal Cord InjuriesHumansMotor NeuronsHyperreflexiaMotoneuronsOperant conditioningPlasticitySpinal cord injuryStretch reflexes

Identifiers

PMID42062016
PMCPMC13138439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.