Evidence map›Paper›PMID 42060779›Full record

ArticleJournal of clinical microbiology2026

Identification of multiple arbovirus infections/exposure in Northeastern Brazil using a multiplex microsphere immunoassay.

Wei-Kung Wang, Eduardo Martins Netto, Szu-Chia Hsieh, Guan-Hua Chen, Melissa Barreto Falcão, Celia Pedroso, Rafaela Mayoral, Roger Costa, Yu-Ching Dai, Rennsilve C Salomon and 5 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei-Kung WangDepartment of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.ORCID 0000-0002-6670-4663
Eduardo Martins NettoLaboratório de Pesquisa em Infectologia (LAPI)-School of Medicine, Universidade Federal da Bahia, Salvador, Brazil.ORCID 0000-0003-1691-6761
Szu-Chia Hsieh *Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Guan-Hua Chen *Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Melissa Barreto FalcãoFundação José Silveira, Salvador, Bahia, Brazil.
Celia PedrosoLaboratório de Pesquisa em Infectologia (LAPI)-School of Medicine, Universidade Federal da Bahia, Salvador, Brazil.
Rafaela MayoralLaboratório de Pesquisa em Infectologia (LAPI)-School of Medicine, Universidade Federal da Bahia, Salvador, Brazil.
Roger CostaLaboratório de Pesquisa em Infectologia (LAPI)-School of Medicine, Universidade Federal da Bahia, Salvador, Brazil.
Yu-Ching DaiDepartment of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Rennsilve C SalomonDepartment of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Jih-Jin TsaiTropical Medicine Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.ORCID 0000-0003-2226-8916
Laíse de MoraesInstituto Gonçalo Moniz -Oswaldo Cruz Foundation (FIOCRUZ), Bahia, Brazil.
Viviane Sampaio BoaventuraInstituto Gonçalo Moniz -Oswaldo Cruz Foundation (FIOCRUZ), Bahia, Brazil.
Ricardo KhouriInstituto Gonçalo Moniz -Oswaldo Cruz Foundation (FIOCRUZ), Bahia, Brazil.
Carlos BritesLaboratório de Pesquisa em Infectologia (LAPI)-School of Medicine, Universidade Federal da Bahia, Salvador, Brazil.ORCID 0000-0002-4673-6991

Funding

Long-term safety and effectiveness of Dengvaxia in the PhilippinesR01AI186073 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI Wei-Kung Wang · 2024 to 2026
$1.5M
Multiplex Serodiagnostic Assays for Pathogenic Arboviruses in BrazilR01AI149502 · NIAID · UNIVERSITY OF HAWAII AT MANOA · PI WANG, WEI-KUNG · 2020 to 2023
$624k
Conselho Nacional de Desenvolvimento Científico e Tecnológico 404193/2019-6National Institute of Allergy and Infectious Diseases R01AI149502National Institute of Allergy and Infectious Diseases R01AI186073NIAID NIH HHS R01 AI149502NIAID NIH HHS R01 AI186073
6 · The paper itself

Abstract

Several mosquito-borne arboviruses, including dengue (DENV), Zika (ZIKV), West Nile (WNV), yellow fever (YFV), and chikungunya (CHIKV) viruses, have caused disease outbreaks of public health concern in the tropics and subtropics. The overlap distribution of these arboviruses and cross-reactivities of antibodies to orthoflavivirus envelope protein underscore the need for a reliable and convenient serological test to distinguish these arboviruses in endemic countries. We developed a multiplex IgG microsphere immunoassay (MIA) using 13 antigens to test 8 panels of samples with well-documented arbovirus infections or vaccination (

Indexed as

Antibodies, ViralArbovirusesArbovirus InfectionsCoinfectionSerologic TestsAntigens, ViralBrazilHumansImmunoassayImmunoglobulin GMicrospheresSensitivity and SpecificityAntibodies, ViralAntigens, ViralImmunoglobulin GarbovirusChikungunya virusdengue virusserosurveillanceZika virus

Identifiers

PMID42060779
PMCPMC13251372

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.