Evidence map›Paper›PMID 42060303›Full record

ArticleJAMA network open2026

Physical Performance Changes Across Race and Region Among Black and White Older Adults.

Srishti Shrestha, William Windham, Hunter C Sylvester, Xiaoqian Zhu, Roland J Thorpe, Priya Palta, A Richey Sharrett, Anna Kucharska-Newton, Thomas H Mosley, Michael E Griswold and 1 more

Abstract read
In one paragraph

Article in JAMA network open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Srishti ShresthaMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.
William WindhamForrest General Hospital Family Medicine Residency Program, Hattiesburg, Mississippi.
Hunter C SylvesterMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.
Xiaoqian ZhuMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.
Roland J ThorpeProgram for Research on Men's Health, Johns Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Priya PaltaDepartment of Neurology, University of North Carolina at Chapel Hill.
A Richey SharrettDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Anna Kucharska-NewtonDepartment of Epidemiology, University of North Carolina at Chapel Hill.
Thomas H MosleyMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.
Michael E GriswoldMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.
B Gwen WindhamMemory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Identifying factors that explain differences in physical performance measures by race and region in the US and whether they are associated with changes over time could inform preventive strategies. Objective: To examine 10-year changes in physical performance across race and race-region among Black and White older adults and whether differences are explained by demographic, cardiovascular, socioeconomic, and cognitive factors. Design, Setting, and Participants: The prospective Atherosclerosis Risk in Communities (ARIC) cohort study recruited participants between 1987 and 1989. This study included participants from 4 US communities in North Carolina, Mississippi, Maryland, and Minnesota who underwent physical performance evaluations initiated in 2011 to 2013 (visit 5 examinations) and in 3 subsequent in-person examinations conducted over a 10-year period through 2022. Data were analyzed from January through May 2025. Exposure: Self-identified race and region. Main Outcomes and Measures: Physical performance was assessed using the Short Physical Performance Battery (SPPB; score range, 0-12, with higher scores indicating better performance). Multivariable generalized estimating equations estimated cross-sectional differences as well as differences in 10-year changes by race and by race and region, adjusting for demographic, cardiovascular, socioeconomic, and cognitive factors. Results: Among 5666 participants (mean [SD] age, 75.4 [5.1] years; 3258 [58%] women), 1233 (22%) self-identified their race as Black and 4433 (78%) self-identified their race as White. Adjusting for demographic, cardiovascular, socioeconomic, and cognitive factors explained observed cross-sectional differences in physical performance between Black participants and White participants. However, 10-year SPPB longitudinal declines were steeper for Black participants compared with White participants (absolute difference, -0.80 points; 95% CI, -1.19 to -0.41 points), even after adjusting for all factors that accounted for cross-sectional differences; this finding met the 0.50-point threshold for a clinically meaningful difference. Between-region declines within races also showed notable differences; for example, SPPB declines were steeper for White Maryland participants compared with White North Carolina participants (absolute difference, -1.14 points; 95% CI, -1.45 to -0.83 points), and declines were steeper for Black Mississippi participants compared with Black North Carolina participants (absolute difference, -1.72 points; 95% CI, -2.65 to -0.78 points). Conclusions and Relevance: In this cohort study of older adults, meaningful racial differences in physical performance declines were not explained by commonly suggested drivers of performance differences. Other unmeasured regional features may explain racial differences in decline in physical performance and warrant investigation.

Indexed as

Black or African AmericanPhysical Functional PerformanceWhiteAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMarylandMinnesotaMississippiNorth CarolinaProspective StudiesUnited States

Identifiers

PMID42060303
PMCPMC13133694

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.