ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2026
Green-synthesized metal oxide nanoparticles enhance the antibacterial activity of Portulaca oleracea through foliar nano-elicitation.
Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acne-associated and other skin-related bacterial infections are increasingly difficult to manage because of antimicrobial resistance and the need for safer therapeutic alternatives. Portulaca oleracea is a medicinal plant with recognized bioactive potential, yet its antibacterial activity can potentially be enhanced through nano-elicitation. Unlike studies that examine nanoparticles as direct antimicrobials, this work investigated green-synthesized metal oxide nanoparticles as foliar elicitors to improve the antibacterial potential of P. oleracea extracts. This approach links sustainable nanoparticle synthesis with medicinal-plant priming to generate extracts with greater activity against acne-associated pathogens. Zinc oxide, magnesium oxide, and alpha-iron oxide nanoparticles were synthesized using aqueous Psidium guajava leaf extract and verified by standard physicochemical characterization. P. oleracea plants received foliar applications of 100 ppm nanoparticle suspensions under greenhouse conditions, after which methanolic aerial-part extracts were evaluated against Staphylococcus aureus, Escherichia coli, and Cutibacterium acnes. Iron oxide treatment produced the strongest response without visible phytotoxicity. By day 25, FeNP-treated plants reached 10.7 ± 0.7 cm in height and 12 ± 1 leaves, compared with 9.1 ± 0.6 cm and 10 ± 1 leaves in untreated controls. Extracts from FeNP-treated plants also showed the highest antibacterial activity, with inhibition zones of 20.0 ± 1.7 mm against S. aureus, 15.7 ± 1.5 mm against E. coli, and 18.3 ± 1.5 mm against C. acnes. These findings show that foliar nano-elicitation, particularly with FeNPs, can enhance plant growth and strengthen the antibacterial potential of P. oleracea. Because phytochemical changes were inferred indirectly from FTIR patterns and antibacterial response rather than direct metabolite quantification, future studies should perform quantitative phytochemical profiling and confirm extract potency through MIC and MBC assays.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.