Evidence map›Paper›PMID 42060234›Full record

ArticleInternational journal of clinical pharmacy2026

Barriers and facilitators for the implementation of medication safety recommendations: focus groups with stakeholders.

Mirthe A M Oude Lansink, Marcia Vervloet, Lise van Tholen, Marloes Dankers, Mette Heringa, Bart J F van den Bemt, Liset van Dijk, Victor J B Huiskes

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Article in International journal of clinical pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mirthe A M Oude LansinkDepartment of Pharmacy, Sint Maartenskliniek, Nijmegen, the Netherlands. m.oudelansink@maartenskliniek.nl.
Marcia VervloetNetherlands Institute for Health Services Research, Utrecht, the Netherlands.
Lise van TholenFaculty of Science and Engineering, Department of Pharmaco Therapy, Groningen Research Institute of Pharmacy, Epidemiology & Economics (PTEE), University of Groningen, Groningen, the Netherlands.
Marloes DankersDutch Institute for Rational Use of Medicine, Utrecht, the Netherlands.
Mette HeringaSIR Institute for Pharmacy Practice and Policy, Leiden, the Netherlands.
Bart J F van den BemtDepartment of Pharmacy, Sint Maartenskliniek, Nijmegen, the Netherlands.
Liset van DijkNetherlands Institute for Health Services Research, Utrecht, the Netherlands.
Victor J B HuiskesDepartment of Pharmacy, Sint Maartenskliniek, Nijmegen, the Netherlands.

Funding

ZonMw 201865006.028.111
6 · The paper itself

Abstract

introductionMultiple medication safety recommendations to reduce preventable medication-related hospitalisations have been introduced in the Netherlands. Still, these hospitalisations remain prevalent. This might be due to suboptimal implementation in clinical practice. Therefore, more insight is needed into barriers and facilitators for the implementation of these medication safety recommendations across healthcare sectors.

aimThis study aimed to identify barriers and facilitators for implementing medication safety recommendations across healthcare sectors from the perspective of various stakeholders.

methodA selection of 17 Dutch medication safety recommendations targeting medications responsible for a large proportion of medication-related hospitalisations was evaluated in focus groups to identify barriers and facilitators to their implementation. These included recommendations for: reducing fall risk in elderly; initiating prophylactic medication; monitoring patients at risk of electrolyte disorders; clarifying responsibilities for patient care; informing patients about alarm symptoms; and prescribing antithrombotics on strict indication. Stakeholders were selected through purposive sampling based on their profession and healthcare sector. Transcripts of audio-recordings were analysed inductively, after which implementation factors were categorised using the Consolidated Framework for Implementation Research.

resultsThirty stakeholders were divided into five focus groups. These included community pharmacists (n = 9), general practitioners (n = 4), hospital pharmacists (n = 3), representatives from healthcare knowledge organisations (n = 3), patient representatives (n = 2), medical specialists (n = 2), nurses (n = 2), and other stakeholders (n = 5). Forty-nine barriers and facilitators were identified. Key themes were lack of specified responsibilities, limited information exchange, local collaboration and protocol adherence. Recommendations with a lower level of implementation often required collaboration with multiple healthcare providers, whereas recommendations with a higher level of implementation were frequently supported by clinical decision support systems.

conclusionA broad range of barriers and facilitators to the implementation of medication safety recommendations was identified. Overall, the findings highlight the need for recommendations with specified responsibilities, improved information exchange, strengthened local collaboration, and increased protocol adherence.

Indexed as

Drug-Related Side Effects and Adverse ReactionsFocus GroupsMedication ErrorsPatient SafetyStakeholder ParticipationHumansNetherlandsPharmacistsDrug-related side effects and adverse reactionsHospitalisationImplementation scienceMedication errorsPatient readmissionQuality of health care

Identifiers

PMID42060234
PMCPMC13369716

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