Evidence map›Paper›PMID 42059954›Full record

ArticleMikrochimica acta2026

Development of a rapid calcium testing strip with metal-enhanced fluorescence for early detection of hypocalcemia in dairy cattle.

Lian Miller, Huiyan Li

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lian MillerCollege of Engineering, University of Guelph, Guelph, ON, N1G2W1, Canada.
Huiyan LiCollege of Engineering, University of Guelph, Guelph, ON, N1G2W1, Canada. huiyanli@uoguelph.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypocalcemia (milk fever) is a severe metabolic disease in dairy cattle, affecting up to 50% of multiparous cows postpartum and leading to significant economic losses and increased risk of secondary disorders. Rapid, low cost, and on-site detection of low blood calcium levels (< 1.1 mM) is needed for timely intervention, yet current diagnostic methods are costly, complex, or require centralized laboratory analysis, delaying treatment. This study addresses the need for a simple, rapid, and cost-effective diagnostic tool by developing a gold nanoparticle-functionalized test strip for the quantification of ionized calcium (Ca

Indexed as

CalciumCattle DiseasesHypocalcemiaReagent StripsAnimalsCattleFemaleFluorescenceFluorescent DyesGoldLimit of DetectionMetal NanoparticlesMilkRapid Diagnostic TestsSpectrometry, FluorescenceCalciumFluorescent DyesGoldReagent StripsBovine milkBovine plasmaCalcium sensingMetal-enhanced fluorescenceOn-site analysisSubclinical hypocalcemia

Identifiers

PMID42059954

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.