Evidence map›Paper›PMID 42059903›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Risk factors and timing of ocular complications after screening for retinopathy of prematurity.

Samantha X Xing, Dylan K Kim, Kriti Joshi Ojha, Lisa A Hark, Nicholas Hyman, Jason D Horowitz, Lauren B Yeager, Steven E Rosenberg, Sonali D Talsania

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha X XingColumbia University Vagelos College of Physicians and Surgeons, 104 Haven Avenue, New York, NY, USA.
Dylan K KimColumbia University Vagelos College of Physicians and Surgeons, 104 Haven Avenue, New York, NY, USA.
Kriti Joshi OjhaEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA.
Lisa A HarkEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA.
Nicholas HymanDepartment of Ophthalmology, New York Medical College, 100 Woods Road Macy Pavilion, Valhalla, NY, USA.
Jason D HorowitzEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA.
Lauren B YeagerEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA.
Steven E RosenbergEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA.
Sonali D TalsaniaEdward S. Harkness Eye Institute, Columbia University Irving Medical Center, 622 W 168th Street, PH18, New York, NY, 10032, USA. st3320@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-4158-364X

Funding

Research to Prevent Blindness Research to Prevent Blindness
6 · The paper itself

Abstract

purposeRetinopathy of prematurity (ROP) remains a leading cause of childhood vision loss, often resulting in long-term complications such as strabismus, amblyopia, and glaucoma. Despite advances in screening, limited data exist on which infants are at highest risk and when these complications typically emerge-an important gap given the nationwide shortage of pediatric ophthalmologists. This study aimed to identify predictors of post-ROP ocular complications and determine the optimal timing and frequency of pediatric ophthalmology follow-up visits.

methodsWe retrospectively reviewed 223 infants who underwent ROP screening between 2018 and 2021 and subsequently followed up with pediatric ophthalmology. The primary outcome was the development of ocular complications following ROP resolution, including their type and timing of detection. Univariate and multivariate logistic regression were used to identify independent risk factors, and Kaplan-Meier analysis assessed time to complication onset.

resultsOf 223 infants, 54 (24.2%) developed at least one ocular complication. The most common were refractive error (17.0%), strabismus (13.9%), and amblyopia (4.5%). Most complications occurred within two years after ROP clearance. Strabismus was diagnosed earliest, followed by refractive error and amblyopia. Longer NICU stay was an independent predictor of ocular complications (OR 1.30, 95% CI 1.04-1.63; p = 0.022).

conclusionsNearly one in four infants developed ocular complications after ROP screening, typically within the first two years. NICU length of stay independently predicted risk, supporting the need for risk-stratified surveillance to ensure timely detection, optimize resource allocation, and reduce preventable vision loss in infants screened for ROP.

Indexed as

Neonatal ScreeningRetinopathy of PrematurityStrabismusVisual AcuityAmblyopiaFemaleFollow-Up StudiesGestational AgeHumansIncidenceInfantInfant, NewbornMaleRetrospective StudiesRisk FactorsTime FactorsOcular complicationsPediatric ophthalmologyPremature infantsRetinopathy of prematurity

Identifiers

PMID42059903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.