Evidence map›Paper›PMID 42059788›Full record

ArticleeLife2026

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Lingli Kong, Ximena Zottig, Johannes Elferich, Nikolaus Grigorieff

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingli KongRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-5808-2649
Ximena ZottigRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-2344-5163
Johannes ElferichRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-9911-706X
Nikolaus GrigorieffRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-1506-909X

Funding

Chan Zuckerberg Initiative 2021-234617 (5022)
6 · The paper itself

Abstract

The exposure of frozen biological samples to the high-energy electron beam in a cryo-electron microscope commonly leads to beam-induced sample motion and distortions. Previously, we described

Indexed as

Cryoelectron MicroscopyImage Processing, Computer-AssistedImaging, Three-DimensionalAnimalsMotionSoftwarecandida albicanscell biologycercopithecus aethiopscryo-EMdistortion correctionimage processingmolecular biophysicsmovie alignmentmus musculusmycoplasma pneumoniaeribosomesaccharomyces cerevisiaestructural biologytwo-dimensional template matching

Identifiers

PMID42059788
PMCPMC13132544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.