Evidence map›Paper›PMID 42059658›Full record

ArticleAntimicrobial agents and chemotherapy2026

LYSG101: a potent chimeric lysin with therapeutic potential for combating

Wen Xiao, Tian Fang, Jiawen Guan, Jie Ren, Mya Thandar, Guanghuai Jin, Menglin Wang, Ning Gan, Fuye Ma, Assaf Raz

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wen XiaoLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Tian FangLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Jiawen GuanLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Jie RenLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Mya ThandarLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Guanghuai JinLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Menglin WangLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Ning GanLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Fuye MaLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.
Assaf RazLysigen, a Precisio Biotix Therapeutics company, Wuhan, Hubei, China.ORCID 0009-0009-5945-2427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysins are peptidoglycan hydrolases with great promise as novel and highly differentiated biotherapeutic agents. Here, we characterize LYSG101, a chimeric lysin active against all

Indexed as

Anti-Bacterial AgentsStaphylococcal InfectionsStaphylococcus aureusAnimalsBiofilmsFemaleHumansMethicillin-Resistant Staphylococcus aureusMiceMicrobial Sensitivity TestsAnti-Bacterial Agentsantimicrobial resistancebiofilmClyOendolysinMRSApeptidoglycan hydrolase

Identifiers

PMID42059658
PMCPMC13231913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.