Evidence map›Paper›PMID 42059463›Full record

ArticleJournal of veterinary internal medicine2026

Treatment of ventricular arrhythmias with oral sotalol in four horses.

Hannah K Junge, Elizabeth G Williams Louie, Katharyn J Mitchell, Colin C Schwarzwald

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hannah K JungeEquine Department, University of Zurich, 8057 Zurich, ZH, Switzerland.
Elizabeth G Williams LouieDepartment of Clinical Sciences, Cornell University, Ithaca, NY 14853, United States.ORCID 0000-0001-7910-8740
Katharyn J MitchellDepartment of Clinical Sciences, Cornell University, Ithaca, NY 14853, United States.
Colin C SchwarzwaldEquine Department, University of Zurich, 8057 Zurich, ZH, Switzerland.

Funding

Graduate Training Program in Comparative MedicineT32OD011000 · OD · CORNELL UNIVERSITY · PI Amanda Marjorie DE MESTRE · 2012 to 2026
$5.7M
NIH HHS T32 OD011000
6 · The paper itself

Abstract

Sustained ventricular arrhythmias (VAs) in horses can require medical intervention. Prompt pharmacological treatment is indicated when the arrhythmia leads to hemodynamic or electrical instability. Established antiarrhythmic treatment of VA in horses includes lidocaine and magnesium, administered parenterally. Other antiarrhythmic agents are used; however, concerns regarding adverse effects, financial restrictions, logistics of administration, and lack of access often limit their use. While anecdotal reports of oral administration of sotalol for treatment of VA in horses exist, sotalol has primarily been described for prevention of recurrent atrial fibrillation or suppression of supraventricular and ventricular ectopy. This case series describes 4 horses with sustained VA treated orally with sotalol. Successful conversion to a predominantly normal sinus rhythm or pre-existing atrial fibrillation was achieved without any adverse effects. Sotalol could be considered as a treatment option in selected, hemodynamically stable cases of VA, especially where other established treatment options are unavailable, ineffective, or unaffordable.

Indexed as

Anti-Arrhythmia AgentsArrhythmias, CardiacHorse DiseasesSotalolTachycardia, VentricularAdministration, OralAnimalsHorsesAnti-Arrhythmia AgentsSotalolantiarrhythmic therapyequineventricular tachycardiaβ-blocker

Identifiers

PMID42059463
PMCPMC13130061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.