Evidence map›Paper›PMID 42059462›Full record

ArticleJournal of veterinary internal medicine2026

Clinical features, risk factors, and outcomes of Bordetella bronchiseptica respiratory infections in dogs diagnosed at a tertiary care institution.

Grace R Marshall, Kelly M Makielski, Aaron K Rendahl, Emily L Coffey

Abstract readObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Grace R MarshallDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, Saint Paul, MN 55108, United States.
Kelly M MakielskiDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, Saint Paul, MN 55108, United States.
Aaron K RendahlDepartmvent of Veterinary and Biomedical Sciences, University of Minnesota, College of Veterinary Medicine, Saint Paul, MN 55108, United States.
Emily L CoffeyDepartment of Veterinary Clinical Sciences, University of Minnesota, College of Veterinary Medicine, Saint Paul, MN 55108, United States.

Funding

National Institutes of Health's National Center for Advancing Translational Sciences K12TR004373Office of the Director of the National Institutes of Health K01-OD031810
6 · The paper itself

Abstract

backgroundBordetella bronchiseptica (Bb) is a common respiratory infection in dogs with potentially serious clinical consequences. A subset of Bb cases require referral to tertiary care institutions, yet these dogs lack characterization. HYPOTHESIS/

objectivesDescribe the clinical features, diagnostic findings, management, and outcomes of dogs diagnosed with Bb infections at a tertiary care institution, and evaluate risk factors associated with severe, refractory, or recurrent Bb infections. ANIMALS: Fifty-nine client-owned dogs diagnosed with Bb infections at a tertiary care hospital.

methodsRetrospective, observational study (1995-2024). Univariable and multivariable logistic regression models were used to identify risk factors associated with negative disease outcomes.

resultsCavalier King Charles Spaniels (CKCS) and Yorkshire Terriers were overrepresented (17.0% and 10.2%, respectively) when compared with hospital admissions from the same period (P <.0001 for both). Nearly 80% of infections were classified as chronic in this population, with a median duration of clinical signs of 30 days. Approximately 40% of cases were classified as severe infections (ie, pneumonia), whereas 54% were classified as refractory. Recurrent Bb infections were uncommon (7%). Mycoplasma spp. coinfections were reported in 37% of cases but were not associated with outcomes. Although no variables were identified as predictors of severe disease, respiratory tract comorbidities (eg, brachycephaly) were associated with refractory infections (P = .04). CONCLUSIONS AND CLINICAL IMPORTANCE: Yorkshire Terriers and CKCS were overrepresented for Bb infections in a referral population, which could indicate underlying risk factors within these breeds. Structural respiratory tract abnormalities may predispose dogs to refractory Bb infections.

Indexed as

Bordetella bronchisepticaBordetella InfectionsDog DiseasesRespiratory Tract InfectionsAnimalsDogsFemaleMaleRecurrenceRetrospective StudiesRisk FactorsTertiary Care CentersCanine infectious respiratory disease complex (CIRDC)Cavalier King Charles SpanielMycoplasmaPneumoniaYorkshire Terrier

Identifiers

PMID42059462
PMCPMC13130056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.