Evidence map›Paper›PMID 42059378›Full record

ArticleAntimicrobial agents and chemotherapy2026

Treatment outcomes of combination versus monotherapy in

Ming-Hang Tsai, Wei-Ping Chen, Chien-Liang Chen, L Kristopher Siu, Ching-Mei Yu, Hung-Sheng Shang, Feng-Yee Chang, Jung-Chung Lin, Ya-Sung Yang, Ching-Hsun Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Infection and drug resistance · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming-Hang TsaiDivision of Infectious, Department of Medicine, Tri-Service General Hospital SongShan Branch, National Defense Medical University, Taipei, Taiwan.
Wei-Ping ChenDivision of Infectious Diseases, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
Chien-Liang ChenDivision of Infectious Diseases, Department of Internal Medicine, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan.
L Kristopher SiuInstitute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.ORCID 0000-0002-9840-3638
Ching-Mei YuDepartment of Pathology, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Hung-Sheng ShangDepartment of Pathology, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Feng-Yee ChangDivision of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Jung-Chung LinDivision of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Ya-Sung YangDivision of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Ching-Hsun WangDivision of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.ORCID 0000-0003-4768-6524

Funding

National Defense Medical University MND-MAB-D-115132Tri-Service General Hospital TSGH_D_113143Tri-Service General Hospital TSGH_D_113181Tri-Service General Hospital TSGH_E_115281
6 · The paper itself

Abstract

A combination therapy (CT) is recommended for

Indexed as

Anti-Bacterial AgentsBacteremiaGram-Negative Bacterial InfectionsStenotrophomonas maltophiliaAgedDrug Therapy, CombinationFemaleHospital MortalityHumansMaleMicrobial Sensitivity TestsMiddle AgedRetrospective StudiesTreatment OutcomeTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug Combinationadverse drug reactionsbacteremiacombination therapymonotherapymortalityStenotrophomonas maltophilia

Identifiers

PMID42059378
PMCPMC13231920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.