Evidence map›Paper›PMID 42059376›Full record

ArticleInfection and immunity2026

STING agonists reduce genital chlamydial infection and attenuate inflammation and pathology.

Xuemei Wang, Cuixiu Wu, Yidan Gao, Lijuan Jiang, Yuanshuo Guo, Na Cui, Qian Wang, Haoneng Tang, Shuping Hou, Chunfu Yang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xuemei Wang *Experimental Center, Guizhou Center for Disease Control and Prevention, Guiyang, China.ORCID 0009-0004-8925-9111
Cuixiu Wu *Department of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Yidan GaoDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Lijuan JiangDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Yuanshuo GuoDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Na CuiDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Qian WangDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Haoneng TangDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Shuping HouDepartment of Dermatovenereology, Tianjin Medical University General Hospital/Tianjin Institute of Sexually Transmitted Disease, Tianjin, China.ORCID 0000-0002-0913-5847
Chunfu YangSchool of Public Health and Emergency Management, School of Medicine, Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0001-7116-0501
Lingli TangDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.ORCID 0009-0002-6223-0875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cGAS-STING pathway is activated during chlamydial infection and plays a critical role in controlling

Indexed as

2’3’-cGAMPChlamydiadiABZIgenital infectionSTING agonist

Identifiers

PMID42059376
PMCPMC13248675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.