Evidence map›Paper›PMID 42059294›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2026

Anal sphincter function in conservatively managed rectal intussusception at long-term follow-up: A prospective anal acoustic reflectometry study with comparison to healthy volunteer data.

Alexander O'Connor, Matthew Davenport, Niels Klarskov, Abhiram Sharma, Dipesh H Vasant, John McLaughlin, Edward Kiff, Karen Telford

Abstract readComparative Study
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander O'ConnorFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-3964-9152
Matthew DavenportFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0003-1341-562X
Niels KlarskovDepartment of Obstetrics and Gynecology, Herlev University Hospital, Herlev, Denmark.ORCID https://orcid.org/0000-0003-1906-3135
Abhiram SharmaFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.
Dipesh H VasantFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.
John McLaughlinFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.
Edward KiffDepartment of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, UK.
Karen TelfordFaculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.

Funding

Royal College of Surgeons of England
6 · The paper itself

Abstract

aimRectal intussusception (RI), proposed to be a progressive condition, is associated with internal sphincter dysfunction. This study examines sphincter function using anal acoustic reflectometry (AAR) at long-term follow-up.

methodsA prospective study of conservatively managed patients attending a tertiary pelvic floor unit. Clinical, AAR and symptom severity data were analysed at baseline and follow-up (>5 years). Patients were grouped into intra-rectal (Oxford I-II) or intra-anal RI (III-IV). Data from asymptomatic volunteers were used to estimate the effect of ageing on AAR parameters.

resultsTwenty-nine patients (27 female; median age: 66 years) were recruited, with follow-up at a median of 66 (IQR: 64-67) months. Twelve were diagnosed with intra-rectal RI and 17 with intra-anal RI at baseline. No patient developed an external rectal prolapse. There were no differences in quality of life, faecal incontinence or constipation symptoms in either group at follow-up (p > 0.05). A non-significant decrease in opening pressure, a measure of internal sphincter function, was seen in both intra-rectal (-4.0 cmH

conclusionThere were no significant changes in patient-reported symptoms or anal sphincter function in conservatively managed RI at follow-up, challenging the concept of a progressive condition with a detrimental impact on sphincter function.

Indexed as

Anal CanalIntussusceptionRectal DiseasesAcousticsAgedCase-Control StudiesConservative TreatmentFecal IncontinenceFemaleFollow-Up StudiesHealthy VolunteersHumansMaleMiddle AgedProspective StudiesQuality of Lifeanal acoustic reflectometryfaecal incontinencerectal intussusceptionrectal prolapse

Identifiers

PMID42059294
PMCPMC13130366

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.