ArticleJournal of medical virology2026
KSHV Genome in Saliva, Whole Blood and Kaposi's Sarcoma Biopsy Specimens in Republic of Congo: Phylogenetic Analysis and an APOBEC3B Mutational Signature.
Gervillien Arnold Malonga, Valentin Leducq, Antoine Fauchois, Dimitry Moudiongui Mboungou Malanda, Patrina Joseph Iloukou Mayakia, Juthèce Private Malanda-Kiminou, Ferdinand Emaniel Brel Got, Fabien Gaël Mouamba, Vincent Calvez, Jean Felix Peko and 2 more
Abstract read
In one paragraphArticle in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Gervillien Arnold MalongaSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.ORCID https://orcid.org/0000-0003-1840-951X Valentin LeducqSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.ORCID https://orcid.org/0000-0002-6817-6227 Antoine FauchoisSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.
Vincent CalvezSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.
Jean Felix PekoFaculté des Sciences de la Santé, Université Marien Ngouabi, Brazzaville, Republic of Congo.
Anne-Geneviève MarcelinSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.ORCID https://orcid.org/0000-0003-4808-8999 Aude JarySorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Pitié-Salpêtrière - Charles Foix, Laboratoire de Virologie, Paris, France.ORCID https://orcid.org/0000-0002-1952-6729 Funding
Agence nationale de recherche sur le Sida et les hépatites virales - Maladies infectieuses émergentes (ANRS-MIE).
6 · The paper itselfAbstract
Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with a variety of diseases and is endemic in Sub-Saharan Africa. We performed KSHV-whole-genome analysis and search for APOBEC-editing to describe genetic diversity in samples issued from an endemic region. We included 15 Congolese samples including 12 saliva and whole blood samples of people living with HIV and 3 KS biopsies samples, to perform KSHV qPCR and NGS Illumina followed by KSHV typing on ORFs K1 and K15. Furthermore, we looked for APOBEC3B-mutations in KSHV-whole-genome sequences. KSHV viral load was detectable in all samples and ranged from 374 to 72799 copies/10
Indexed as
BloodCytidine DeaminaseGenome, ViralHerpesvirus 8, HumanMinor Histocompatibility AntigensPhylogenySalivaSarcoma, KaposiAdultBiopsyCongoDNA, ViralFemaleGenetic VariationHIV InfectionsHumansAPOBEC3B protein, humanCytidine DeaminaseDNA, ViralMinor Histocompatibility AntigensAPOBEC3B mutationsCongoKSHVphylogenetic analysiswhole‐genome sequencing
Identifiers
PMID42059071
PMCPMC13129949
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