Evidence map›Paper›PMID 42059016›Full record

ArticleJournal of global health2026

Prevalence and types of lower limb conditions in Nepal.

Lucy Gates, Amos R Channon, Alex Dickinson, Basu D Pandey, Abhinav Vaidya, Binit Vaidya, Yeti Raj Niraula, Rabindra Baskota, Shweta Nakarmi, Cheryl Metcalf and 4 more

Abstract read
In one paragraph

Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lucy GatesSchool of Healthcare Enterprise & Innovation, University of Southampton, Southampton, UK.
Amos R ChannonExceed Research Network, Lisburn, UK.
Alex DickinsonExceed Research Network, Lisburn, UK.
Basu D PandeyDEJIMA Infectious Disease Research Alliance (DIDA), Nagasaki University, Japan.
Abhinav VaidyaDepartment of Community Medicine, Kathmandu Medical College Public Limited, Kathmandu, Nepal.
Binit VaidyaNational Center for Rheumatic Diseases, Kathmandu, Nepal.
Yeti Raj NiraulaTechnical Unit, Rehabilitation, Humanity and Inclusion, Syria Mission, Raqqa City, Nepal.
Rabindra BaskotaLeprosy Control and Disability Management Section, Ministry of Health and Population, Nepal.
Shweta NakarmiDepartment of Rheumatology, National Center for Rheumatic Diseases, Kathmandu, Nepal.
Cheryl MetcalfSchool of Healthcare Enterprise & Innovation, University of Southampton, Southampton, UK.
Kate WardMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Alan SilmanNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Anthony WoolfClinical and Molecular Osteoporosis Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Mahesh C PuriCenter for Research on Environment Health and Population Activities (CREHPA), Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lower limb conditions (LLCs) are a major cause of pain, disability, and loss of livelihood globally, yet their prevalence and functional impacts in low- and middle-income countries, including Nepal, remain poorly described. Methods: We conducted a cross-sectional, community-based survey in three Nepali districts representing plains, hills, and mountains. Of 2525 screened households, the first 500 adults with self-selected LLCs were interviewed using structured questionnaires adapted from validated tools (Global Alliance for Musculoskeletal Health, COPCORD, Washington Group, WHODAS 2.0). Descriptive statistics summarised condition type, pain location, activity limitations, employment impact, and comorbidities. χ Results: Of 2525 households, 671 (26.6%, 95% CI = 24.9-28.3) reported a member with an LLC; 11.2% (95% CI = 10.5-12.0) of adults were affected. Among 500 participants surveyed (mean age 57 years; 65% female), pain/discomfort was most common (97%), mainly in the knee (74%) and foot/ankle (48%). Across participants, 628 LLCs were reported; conditions included injury/trauma (19%), deformity (7%), wounds (1%), and amputation (<1%). Prevalence varied by district. Functional limitations were substantial: 82% with pain and all with amputation reported severe activity restriction. Ten percent were unemployed, mostly due to health, and >70% of those doing household work had left other jobs because of their LLC. Conclusions: This study offers preliminary, population-based estimates of person-reported LLCs across three ecological zones in Nepal. Musculoskeletal pain was most common, often multi-site and substantially limiting daily activities and employment. While findings highlight the impact of LLCs on well-being and livelihoods, they remain exploratory due to limited geographic scope and self-reporting. Larger, nationally representative studies are needed to confirm these results, differentiate chronic from transient pain, and guide rehabilitation and prevention strategies.

Indexed as

Lower ExtremityMusculoskeletal DiseasesAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNepalPrevalenceSurveys and Questionnaires

Identifiers

PMID42059016
PMCPMC13136662

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.