Evidence map›Paper›PMID 42058966›Full record

ArticleMaterials today. Bio2026

Biomimetic villi-crypt scaffold-on-chip with tunable mechanical properties for intestinal epithelium modeling.

Lorenzo Zavagna, Marta R Casanova, Lara Pierantoni, Mariana R Carvalho, Joana Silva-Correia, Teresa Macchi, Fabiola Troisi, Roberto Giovannoni, Rui L Reis, Serena Danti and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lorenzo ZavagnaDoctoral School in Life Sciences, University of Siena, Siena, Italy.
Marta R Casanova3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.
Lara Pierantoni3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.
Mariana R Carvalho3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.
Joana Silva-Correia3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.
Teresa MacchiDepartment of Translational Researches and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Fabiola TroisiDepartment of Biology, University of Pisa, Pisa, Italy.
Roberto GiovannoniDepartment of Biology, University of Pisa, Pisa, Italy.
Rui L Reis3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.
Serena DantiDepartment of Civil and Industrial Engineering, University of Pisa, Pisa, Italy.
J Miguel Oliveira3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Rua Ave 1, Edifício 1 (Sede), Barco, Guimarães, 4805-694, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The small intestine possesses a complex architecture and microenvironment. Current

Indexed as

Digital light processing (DLP) 3D printingIntestinal epithelium modelingMicrofluidic deviceProteomic analysisVilli-crypt scaffold

Identifiers

PMID42058966
PMCPMC13123397

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.