Evidence map›Paper›PMID 42058961›Full record

ArticleMaterials today. Bio2026

Mechanical cues regulate

Qian Liu, Kai Chen, Shaoshan Pan, Tao Zhang, Qian Wang, Jiaying Zhu, Jin Zhang, Xiaohua Jiang, Haiying Jia, Shengxia Zheng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qian LiuDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Kai ChenDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Shaoshan PanDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Tao ZhangJiangsu Hernrrie Biological and Medical Technology Company, Taizhou, China.
Qian WangDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Jiaying ZhuDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Jin ZhangJiangsu Hernrrie Biological and Medical Technology Company, Taizhou, China.
Xiaohua JiangDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Haiying JiaThe Ninth Medical Center of Chinese People's Liberation Army General Hospital, Beijing, China.
Shengxia ZhengDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.
Tianzhi LuoDepartment of Modern Mechanics, Reproductive Medicine Center, The First Affiliated Hospital, State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine mechanical properties, particularly tissue stiffness, are dynamically regulated during the embryo implantation window to ensure optimal mechanocompatibility. However, maternal aging and fibrotic pathologies, such as adenomyosis and intrauterine adhesions, disrupt this balance, leading to increased stromal stiffness due to abnormal extracellular matrix (ECM) deposition and crosslinking. In this study, we simulated various uterine environments

Indexed as

Actin cytoskeletonEmbryo implantationHydrogelSubstrate stiffnessTraction force

Identifiers

PMID42058961
PMCPMC13123377

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.