Evidence map›Paper›PMID 42058903›Full record

ArticleiScience2026

A non-invasive method to genotype cephalopod sex by quantitative PCR.

Frederick A Rubino, Gabrielle C Coffing, Connor J Gibbons, Scott T Small, Thomas Desvignes, Jeffrey Pessutti, Ann M Petersen, Alexander Arkhipkin, Zhanna Shcherbich, John H Postlethwait and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Frederick A RubinoDepartment of Biology, Whitehead Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
Gabrielle C CoffingInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
Connor J GibbonsThe Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA.
Scott T SmallInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
Thomas DesvignesDepartment of Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
Jeffrey PessuttiNational Oceanographic and Atmospheric Administration, NOAA Fisheries, Northeast Fisheries Science Center, James J. Howard Marine Sciences Laboratory, Highlands, NJ, USA.
Ann M PetersenNational Oceanographic and Atmospheric Administration, NOAA Fisheries, Northeast Fisheries Science Center, James J. Howard Marine Sciences Laboratory, Highlands, NJ, USA.
Alexander ArkhipkinFisheries New Zealand, Wellington, New Zealand.
Zhanna ShcherbichFalkland Islands Fisheries Department, Stanley, Falkland Islands.
John H PostlethwaitInstitute of Neuroscience, University of Oregon, Eugene, OR, USA.
Andrew D KernInstitute of Ecology and Evolution, University of Oregon, Eugene, OR, USA.
Tessa G MontagueThe Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA.

Funding

Deep learning for population geneticsR01HG010774 · NHGRI · UNIVERSITY OF OREGON · PI ANDREW D KERN · 2020 to 2026
$3.2M
Mechanisms of Sex Determination in ZebrafishR35GM139635 · NIGMS · UNIVERSITY OF OREGON · PI POSTLETHWAIT, JOHN H. · 2021 to 2025
$1.9M
Computational Population GeneticsR35GM148253 · NIGMS · UNIVERSITY OF OREGON · PI ANDREW D KERN · 2023 to 2026
$1.5M
NHGRI NIH HHS R01 HG010774NIGMS NIH HHS R35 GM139635NIGMS NIH HHS R35 GM148253
6 · The paper itself

Abstract

Coleoid cephalopods (cuttlefish, octopus, and squid) are emerging model organisms in neuroscience, development, and evolutionary biology and are of major economic importance in global fisheries. However, they are notoriously difficult and expensive to culture. The ability to determine sex early in development would enable more efficient and sustainable population management in both laboratory and wild settings. Here, we report a non-invasive method to genotype the sex of dwarf cuttlefish (

Indexed as

Biological sciencesBiological sciences research methodologiesGenotyping

Identifiers

PMID42058903
PMCPMC13122204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.