Evidence map›Paper›PMID 42058875›Full record

ArticleResuscitation plus2026

Mechanical versus manual chest compression in cardiac arrest: a systematic review.

Helen Pocock, Tonia C Nicholson, Lukasz Szarpak, Jasmeet Soar, Katherine M Berg, International Liaison Committee on Resuscitation Advanced Life Support Task Force

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mechanical and manual cardiopulmonary resuscitation in traumatic cardiac arrest: a retrospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helen PocockSouth Central Ambulance NHS Foundation Trust, Bicester, UK.
Tonia C NicholsonWaikato Hospital, Hamilton, New Zealand.
Lukasz SzarpakHenry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA.
Jasmeet SoarIntensive Care Unit, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
Katherine M BergDivision of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
International Liaison Committee on Resuscitation Advanced Life Support Task Force

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early high-quality cardiopulmonary resuscitation (CPR) is crucial for survival following cardiac arrest. To-date, ILCOR has suggested against routine use of mechanical chest compressions, reserving its use for settings where manual compressions are difficult to continue. Due to awareness of new trial data, this review was conducted to inform international treatment recommendations. Methods: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Web of Science and the registry platform ClinicalTrials.Gov from inception to 21st October 2025. Only randomised and quasi-randomised controlled trials were included. Critical outcomes of interest were survival with good neurological outcome, survival and quality of life. Important outcomes included ROSC, survival to hospital admission and adverse events. We assessed risk of bias using the Cochrane Risk of Bias-2 tool and evaluated certainty using the GRADE approach. Results: We identified 14 articles reporting results from 11 trials and including a total of 14,565 patients. Substantial methodological and clinical heterogeneity between the studies precluded meta-analysis. The three largest trials (11,291 patients in total), providing low to moderate certainty evidence, all showed no benefit or harm overall from mechanical compressions compared with manual compressions. Lower-certainty evidence from other smaller trials was conflicting, with some showing benefit and some showing harm from a mechanical compression approach. Conclusions: Existing trials do not show a benefit from the use of mechanical compressions, compared with manual compressions. These findings support the current treatment recommendations that advise against the routine use of mechanical chest compression devices.

Indexed as

Advanced life supportCardiac arrestCardiopulmonary resuscitationMechanical chest compressionsSystematic review

Identifiers

PMID42058875
PMCPMC13122787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.