Electrochemically driven strain-release dearomative (3 + 2) cyclization for the synthesis of bicyclo[2.1.1]hexane-fused polycyclic spiroindolines.

Yanren Zhu, Enfan Pu, Shaoxiong Yang, Dongbo Zhao, Qi Xu, Piaopiao Jiang, Xiong Li, Hongbin Zhang, Jingbo Chen

Abstract read

In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanren ZhuKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Enfan PuKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Shaoxiong YangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Dongbo ZhaoKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.ORCID https://orcid.org/0000-0002-0927-4361

Qi XuKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Piaopiao JiangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Xiong LiKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.

Hongbin ZhangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.ORCID https://orcid.org/0000-0002-2516-2634

Jingbo ChenKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Key Laboratory of Cross-Border Infectious Disease Control and Prevention and Novel Drug Development, School of Chemical Science and Technology, School of Pharmacy, Yunnan University Kunming 650500 China zhanghb@ynu.edu.cn chenjb@ynu.edu.cn.ORCID https://orcid.org/0000-0001-7223-7857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spiroindolines are ubiquitous structural motifs in natural products and biologically active compounds, making the development of reliable synthetic methods for their construction highly important to the synthetic chemistry community. Moreover, the synthesis of polycyclic compounds featuring C(sp

Identifiers

PMID42058820

DOI10.1039/d6sc01271j

PMCPMC13122068

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.