ArticleFrontiers in nutrition2026
Association of logarithmic lymphocyte-albumin product with active tuberculosis in children and adolescents.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Active tuberculosis (ATB) in children and adolescents remains a major diagnostic challenge. Inflammation, nutrition, and immune status are closely linked to tuberculosis (TB) progression. We therefore proposed a novel biomarker, the logarithmic lymphocyte-albumin product (logLAP), integrating immune and nutritional indicators, and investigated its association with ATB in children and adolescents. Methods: This retrospective study included 1,080 participants aged <18 years. Participants were classified into ATB ( Results: Compared with non-TB controls, ATB patients exhibited significantly lower logLAP levels (4.07 ± 0.55 vs. 4.39 ± 0.47, Conclusion: As a biomarker integrating immune-nutritional status, logLAP exhibits a robust inverse association with ATB infection in children and adolescents aged ≥8 years with normal or moderately impaired immune function, supported by comprehensive analyses.
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