Evidence map›Paper›PMID 42058709›Full record

ArticleFrontiers in nutrition2026

Relationship between iodine nutritional status and low handgrip strength in a Northwestern Chinese cohort: construction of a predictive nomogram model.

Xiao Liu, Tao Zhang, Songbo Fu, Donghu Zhen, Jingfang Liu, Haixia Qi, Chengxu Ma, Zhongyan Shan, Lihua Ma

Abstract read
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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xiao Liu *Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Tao Zhang *The 940th Hospital of Chinese People's Liberation Army, Lanzhou, China.
Songbo FuDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Donghu ZhenDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Jingfang LiuDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Haixia QiDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Chengxu MaDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.
Zhongyan ShanDepartment of Endocrinology and Metabolic Diseases, The First Hospital of China Medical University, Shenyang, China.
Lihua MaDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Grip strength is a key marker for sarcopenia screening, yet the influence of iodine nutritional status on low grip strength (LGS) remains poorly understood. Methods: This cross-sectional study analyzed 810 community-dwelling adults in Lanzhou, China, randomly assigned to training ( Results: LGS prevalence was 18.8% in the training cohort. Multivariate analysis showed female sex (OR = 0.34), greater height (OR = 0.94), and excessive iodine (OR = 0.36) were inversely associated with LGS, whereas age (60-74 years: OR = 2.20; ≥75 years: OR = 9.73), smoking (OR = 3.20), and SP (OR = 1.02) correlated with higher LGS odds. The nomogram demonstrated moderate discrimination (AUC: 0.723 training, 0.662 validation) with good calibration (Brier scores: 0.134 training, 0.147 validation; H-L Conclusion: The nomogram provides a practical, objective tool for early identification of individuals at high probability of LGS. Moderate-to-high UIC is associated with LGS odds, particularly in euthyroid adults. This model may guide targeted screening and interventions in community settings. In the cross-sectional design, causal inferences cannot be drawn; Further research is warranted to elucidate these complex relationships.

Indexed as

determinantslow grip strengthpredictive nomogramrestricted cubic spline analysisurinary iodine concentration

Identifiers

PMID42058709
PMCPMC13120904

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.