ArticleJCEM case reports2026
Fatal metformin-associated lactic acidosis in a healthy woman after massive overdose.
Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Metformin is widely prescribed for type 2 diabetes mellitus and is generally considered safe. However, metformin-associated lactic acidosis (MALA) is a rare but potentially fatal complication. Although typically associated with renal or hepatic dysfunction, intentional overdose can also lead to severe acidosis and high mortality. A 42-year-old woman with no medical history ingested 12 g of metformin in a suicide attempt. She presented with stable vital signs and normal renal and hepatic function. Initial arterial blood gas showed metabolic acidosis (pH 7.21, HCO
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