Evidence map›Paper›PMID 42058696›Full record

ArticleJCEM case reports2026

Channelopathy linking

Saran Dejprapasorn, Sunti Limumpornpetch, Watchara Lohawijarn, Pongsakorn Choochuen, Wongsakorn Chaochankit, Padiporn Limumpornpetch

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saran DejprapasornEndocrinology and Metabolism Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0009-0000-1214-3891
Sunti LimumpornpetchCardiology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0009-0008-7222-232X
Watchara LohawijarnCardiology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0000-0002-7229-375X
Pongsakorn ChoochuenTranslational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0000-0002-0739-3885
Wongsakorn ChaochankitDivision of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0000-0003-2202-7426
Padiporn LimumpornpetchEndocrinology and Metabolism Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.ORCID https://orcid.org/0000-0003-2205-3616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary aldosteronism (PA) typically presents with hypertension and hypokalemia; however, its presentation as life-threatening ventricular arrhythmias is rare and often underrecognized. We report a case of a 30-year-old woman who presented with polymorphic ventricular tachycardia manifesting as torsades de pointes. Laboratory findings revealed persistent hypokalemia, metabolic alkalosis, suppressed renin, and inappropriately elevated aldosterone. Because recurrent malignant arrhythmia conferred a high immediate risk of sudden cardiac death, genetic testing for inherited arrhythmia syndromes was initiated, and an implantable cardioverter-defibrillator was implanted for secondary prevention before genetic confirmation became available. Endocrine evaluation proceeded concurrently and ultimately established the diagnosis of PA. Subsequent genetic analysis identified a pathogenic splice-site variant in

Indexed as

KCNH2 mutationlong QT syndrome type 2primary aldosteronismtorsades de pointesventricular arrhythmia

Identifiers

PMID42058696
PMCPMC13122025

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.