Evidence map›Paper›PMID 42058650›Full record

ReviewInternational journal of microbiology2026

Prevalence and Risk Factors of Fluoroquinolone Resistance in Major Bacterial Pathogens: A Systematic Review and Meta-Analysis.

I Made Bayu Anggriawan, Ike Dhiah Rochmawati

Abstract readReview
In one paragraph

Review in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

I Made Bayu AnggriawanSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK, gla.ac.uk.ORCID https://orcid.org/0009-0003-6047-0581
Ike Dhiah RochmawatiSchool of Health and Wellbeing, University of Glasgow, Glasgow, UK, gla.ac.uk.ORCID https://orcid.org/0000-0002-2497-7399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The widespread use of fluoroquinolones for the treatment of Gram-negative bacterial infections has contributed to the rising prevalence of antimicrobial resistance. However, limited studies have systematically analyzed the prevalence of fluoroquinolone resistance (FQR) and its associated risk factors. Methods: A systematic review and meta-analysis were conducted, screening studies published between January 1, 2014, and October 31, 2024, from the PubMed, Medline, Embase, and CINAHL databases. Studies were included based on the following criteria: observational designs, evaluation of Gram-negative bacteria for FQR in human subjects, and investigation of FQR and associated risk factors. Data analysis, including pooled prevalence estimation and odds ratio calculation, was performed using R Studio (Version 4.2.3) with the metafor package. Heterogeneity among studies was assessed using Results: A total of 24 studies were included in the systematic review and meta-analysis. The pooled prevalence of FQR across pathogens was 35% (95% CI: 30%-40%), with species-specific rates of Discussion: Although the overall prevalence of FQR was modest, increasing trends in

Indexed as

antimicrobial resistanceEscherichia colifluoroquinolone resistanceKlebsiella spp.Mycobacterium tuberculosisodds ratio: meta-analysisprevalenceProteus spp.Pseudomonas aeruginosarisk factorssystematic review

Identifiers

PMID42058650
PMCPMC13122566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.