Evidence map›Paper›PMID 42058624›Full record

ReviewFrontiers in allergy2026

Hereditary α-tryptasemia; a review of mechanisms linking α-tryptase gene dosage to intestinal homeostasis and immunopathology.

Ilaria M Simeone, Michelle Galeas-Pena, Katelyn White, Brandy Sullivan, Alexandra Morelli, Jocelyn A Silvester, Liza Konnikova, Amelie Therrien, Sarah C Glover

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ilaria M Simeone *Department of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.
Michelle Galeas-Pena *Department of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.
Katelyn WhiteDepartment of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.
Brandy SullivanDepartment of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.
Alexandra MorelliDepartment of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.
Jocelyn A SilvesterCeliac Center, Department of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Liza KonnikovaDepartments of Pediatrics, Immunobiology and Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, United States.
Amelie TherrienCeliac Center, Department of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Sarah C GloverDepartment of Medicine, Section of Gastroenterology, Tulane University, New Orleans, LA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary α-tryptasemia (HαT) is a genetic trait characterized by increased

Indexed as

celiac diseasedisease modificationgastrointestinal tractgene dosagehereditary α-tryptasemiainflammatory bowel diseasemast cellstryptase

Identifiers

PMID42058624
PMCPMC13121348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.