Evidence map›Paper›PMID 42058600›Full record

ArticleMolecular therapy. Oncology2026

Oncolytic virotherapy mobilizes tumor-resident, granzyme B-producing bystander CD4

Shuai Yue, Junjian He, Shusen Ye, Yao Lin, Yang Yang, Yaxing Hao, Texi Liang, Ding Qiu, Kaiyi Li, Chunyang Xie and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Shuai YueCancer Center, Daping Hospital and Army Medical Center of PLA, Army Medical University (Third Military Medical University), Chongqing 400042, China.
Junjian HeInstitute of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Shusen YeInstitute for Immunology and Pathogenesis, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Yao LinDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, China.
Yang YangGuangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangdong 510515, China.
Yaxing HaoInstitute of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Texi LiangGuangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangdong 510515, China.
Ding QiuInstitute for Immunology and Pathogenesis, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Kaiyi LiInstitute for Immunology and Pathogenesis, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Chunyang XieGuangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangdong 510515, China.
Hairu WangInstitute of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Wenwen XiInstitute of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Xiaofan YangGuangdong Province Key Laboratory of Immune Regulation and Immunotherapy, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangdong 510515, China.
Yanli XiongCancer Center, Daping Hospital and Army Medical Center of PLA, Army Medical University (Third Military Medical University), Chongqing 400042, China.
Yu XuCancer Center, Daping Hospital and Army Medical Center of PLA, Army Medical University (Third Military Medical University), Chongqing 400042, China.
Wenyue XuDepartment of Pathogenic Biology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Yi YangDepartment of Rheumatology and Immunology, Center for Immune Ageing and Rejuvenation, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Guozhong ZhangKey Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Jing ZhaoKey Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Lilin YeInstitute of Immunology, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Mengxia LiCancer Center, Daping Hospital and Army Medical Center of PLA, Army Medical University (Third Military Medical University), Chongqing 400042, China.
Xiangyu ChenDepartment of Rheumatology and Immunology, Center for Immune Ageing and Rejuvenation, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer are at elevated risk of life-threatening infections due to immunosuppression caused by both malignancy and its treatments, which compromises pre-existing anti-microbial immune memory established by prior infection or vaccination. Despite this systemic suppression, pathogen-specific memory T (T

Indexed as

anti-microbial therapybystander T cellCD4+ T cellmemory T cellMT: Regular Issueoncolytic virus

Identifiers

PMID42058600
PMCPMC13122683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.