ArticleJournal of transplantation2026
Frailty and Early Extubation Independently Influence Postoperative Recovery Following Liver Transplantation-A Retrospective Cohort Study.
Article in Journal of transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Frailty and Early Extubation Independently Influence Postoperative Recovery Following Liver Transplantation-A Retrospective Cohort Study.Journal of transplantation · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Frailty and perioperative management critically influence outcomes following liver transplantation (LT). The liver frailty index (LFI) objectively assesses frailty, while early extubation (EE) has been linked to enhanced recovery in surgical patients. However, the associations of frailty and EE with postoperative outcomes in LT remain unclear. Methods: This retrospective cohort study included adult LT recipients at a tertiary care center between 1/2019 and 7/2023. Patients were classified as frail (LFI ≥ 4.5) or nonfrail (LFI < 4.5) and stratified by EE versus delayed extubation (DE). Primary outcomes were EE rate, ICU length of stay (LOS), and hospital LOS. Linear regression models adjusted for age, gender, BMI, MELD, transplant type, and liver disease etiology. Results: Of 158 postliver transplant patients, 38 (24.1%) were frail. Frail patients had longer ICU LOS (33.2 vs. 4.2 days, Conclusions: Our study demonstrated that EE significantly shortens ICU and hospital stays in postliver transplant patients with pretransplant frailty. These findings underscore the importance of incorporating EE protocols in this high-risk population and warrant further investigation into strategies that facilitate implementation to optimize clinical outcomes.
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