ArticleInfection and drug resistance2026
Use of the Proportion of Neutrophils in Bronchoalveolar Lavage Fluid for Rapid Diagnosis of Bacterial Pneumonia in Children.
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Currently-available conventional diagnostic tests to identify the causative pathogen of community-acquired pneumonia in children have several limitations. However, the lack of timely and accurate etiological diagnosis could substantially affect childhood pneumonia outcomes. Therefore, this study assessed the efficacy of cytological analysis of bronchoalveolar lavage fluid (BALF) in rapidly distinguishing between bacterial and non-bacterial pneumonia in paediatric patients. Patients: We enrolled patients with community-acquired pneumonia who underwent bronchoalveolar lavage at the Affiliated Hospital of Guangdong Medical University. Pathogens were detected in the BALF, and BALF cytological analysis was performed. Results: Overall, 154 patients were enrolled, among whom 141 had pneumonia (68 severe cases), with 116 cases of bacterial pneumonia and 25 cases of viral pneumonia. The bacterial pneumonia group exhibited a significantly higher neutrophil percentage in the BALF (BALF-NE%) than the viral pneumonia group (p<0.001). Additionally, 100% (13/13), 96.0% (24/25), and 89.7% (104/116) of cases in the control, viral pneumonia, and bacterial pneumonia groups had a BALF-NE% ≤10%, ≤30%, and >30%, respectively. The area under the receiver operating characteristics curve for diagnosing bacterial pneumonia using BALF-NE% was 0.986 (95% confidence interval: 0.963-1.000, standard error: 0.012) (p<0.0001), surpassing that of the white blood cell count, NE%, C-reactive protein level, and procalcitonin level. When setting the threshold to BALF-NE% >28%, the sensitivity and specificity for diagnosing bacterial pneumonia were 98.8% and 94.1%, respectively. Among patients with pneumonia caused by Conclusion: The BALF-NE% outperforms conventional diagnostic indicators and allows reliable, rapid differentiation between bacterial and viral pneumonia in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.