Evidence map›Paper›PMID 42058320›Full record

ArticleIDCases2026

Necrosis of the diaphragm pleural empyema and pneumomediastinum as rare complications of appendicitis: A case report.

Elias Karam, Antoine Legras, Guillaume Brénugat, Nicolas Michot, Martine Ferrandière, Urs Giger-Pabst, Mehdi Ouaïssi

Abstract readCase Reports
In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Elias KaramDepartment of Digestive, Oncological, Endocrine, Hepato-Biliary and Pancreatic Surgery, and Liver Transplantation - Trousseau Hospital, Avenue de la République, Tours F37044, France.
Antoine LegrasDepartment of Vascular, Thoracic and Cardiac Surgery - Trousseau Hospital, Avenue de la République, Tours F37044, France.
Guillaume BrénugatDepartment of Digestive, Oncological, Endocrine, Hepato-Biliary and Pancreatic Surgery, and Liver Transplantation - Trousseau Hospital, Avenue de la République, Tours F37044, France.
Nicolas MichotDepartment of Digestive, Oncological, Endocrine, Hepato-Biliary and Pancreatic Surgery, and Liver Transplantation - Trousseau Hospital, Avenue de la République, Tours F37044, France.
Martine FerrandièreIntensive Care Unit, University Hospital of Tours - Trousseau Hospital, Avenue de la République, Tours F37044, France.
Urs Giger-PabstUMR1327 ISCHEMIA, Membrane signaling and inflammation in reperfusion injuries", Université de Tours, 10, Bd Tonnellé, Tours 37000, France.
Mehdi OuaïssiDepartment of Digestive, Oncological, Endocrine, Hepato-Biliary and Pancreatic Surgery, and Liver Transplantation - Trousseau Hospital, Avenue de la République, Tours F37044, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Appendicitis is one of the most common surgical emergencies in general surgery. To our knowledge, this is the first reported case of diaphragmatic necrosis associated with appendicitis. Case: A 38-year-old male north African patient with no past medical history presented with fever and right lower quadrant pain, for which he started oral self-medication with ibuprofen. Clinical and radiological examinations revealed perforated appendicitis with right-sided pleural empyema and pneumomediastinum. During the initial surgical procedure, we performed an appendicectomy, inserted a chest tube and administered a broad-spectrum antibiotic therapy. The following day, respiratory failure occurred, necessitating right sided thoracoscopy. This revealed diaphragmatic necrosis, which was treated by excision and tension-free suturing after conversion to open thoracotomy. Six days later, persistent sepsis necessitated a new exploratory laparotomy and a right-sided hemicolectomy with an ileocolostomy to treat colonic necrosis. The postoperative course was uneventful, and the patient was discharged one month after admission. Bowel continuity was restored six months later. After a one-and-a-half-year follow-up, the patient remained healthy with no long-term physical impairment. Conclusion: To the best of our knowledge, this is the first case of acute appendicitis complicated by diaphragmatic necrosis, empyema and pneumomediastinum to be reported in the medical literature. The pleural empyema and diaphragmatic defect were treated by conversion from thoracoscopy to thoracotomy and direct suture.

Indexed as

Acute appendicitisComplicationDiaphragmEmpyemaNecrosis

Identifiers

PMID42058320
PMCPMC13122659

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