Evidence map›Paper›PMID 42058068›Full record

Trial reportFrontiers in public health2026

Effects of mindfulness yoga intervention on physical function, anxiety, inflammatory response, and relapse intention in methamphetamine addicts: a 24-week randomized controlled trial.

Su Xia Chen, Zhi Xue Lyu, Zong Ji Hao, Qiang Tang, Wan Jun Li

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Su Xia ChenSchool of Educational Science, Xinjiang Normal University, Xinjiang, Urumqi, China.
Zhi Xue LyuBiology Teaching and Research Group, Chongqing Tongnan Experimental High School, Chongqing, China.
Zong Ji HaoSchool of Physical Education, Southwest University, Chongqing, China.
Qiang TangBiology Teaching and Research Group, Chongqing Tongnan Experimental High School, Chongqing, China.
Wan Jun LiSchool of Educational Science, Xinjiang Normal University, Xinjiang, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methamphetamine (MA) addiction is a chronic relapsing disorder that impairs physical health, induces mental distress (e.g., anxiety), and triggers abnormal inflammatory and neurotransmitter responses, all contributing to high relapse rates. Mindfulness and yoga interventions may alleviate psychological distress and improve physical well-being in substance users; however, few studies have systematically investigated their comprehensive effects on physical function, inflammatory markers, neurotransmitter balance, and relapse intention in MA addicts, leaving a gap in non-pharmacological interventions for this population. Objective: This randomized controlled trial aimed to investigate the effects of a 24-week yoga intervention integrated with mindfulness components on multiple health outcomes among individuals with methamphetamine use disorder, ncluding physical function (assessed by Functional Movement Screening [FMS], reaction time, sleep quality, subjective fatigue, and creatine kinase [CK]), anxiety, inflammatory response (tumor necrosis factor- Methods: Eighty MA addicts meeting DSM-5 criteria were randomly assigned to an experimental group ( Results: Following the 24-week intervention, the experimental group demonstrated significant improvements in sleep quality (PSQI score reduced from 14.32 to 8.41), anxiety levels (BAI score decreased), FMS total score (increased from 9.24 to 12.12), and reaction time (improved from 0.59 s to 0.48 s) compared to baseline and controls ( Conclusion: Compared with a traditional relaxation and stretching control condition, mindfulness yoga intervention demonstrated superior efficacy in improving physical function, sleep quality, and reaction ability of MA addicts. These findings support mindfulness yoga as a promising non-pharmacological intervention for MA addiction rehabilitation. Clinical trial registration: https://www.chictr.org.cn/showproj.html?proj=40393, Unique Identifier is ChiCTR1900024439.

Indexed as

Amphetamine-Related DisordersAnxietyInflammationMethamphetamineMindfulnessYogaAdultFemaleHumansMaleMiddle AgedRecurrenceMethamphetamineanxietyinflammatory responsemethamphetamine addictsmindful yoganeurotransmittersphysical functionrelapse intention

Identifiers

PMID42058068
PMCPMC13121296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.