Evidence map›Paper›PMID 42057923›Full record

ArticleInternational journal of general medicine2026

Risk Factors for Cardiac Rupture After Acute Myocardial Infarction and Development of a Risk Prediction Model.

Jianfang Gao, Peipei Jia, Zhibin Hong, Yinghong Liu, Liping Liang, Li Zhang

Abstract read
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Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jianfang GaoThe First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou City, Gansu Province, 730000, People's Republic of China.
Peipei JiaThe First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou City, Gansu Province, 730000, People's Republic of China.
Zhibin HongCardiovascular Medicine, Tianshui First People's Hospital, Tianshui City, Gansu Province, 741000, People's Republic of China.
Yinghong LiuCardiovascular Medicine, Tianshui First People's Hospital, Tianshui City, Gansu Province, 741000, People's Republic of China.
Liping LiangThe First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou City, Gansu Province, 730000, People's Republic of China.ORCID 0009-0004-8913-743X
Li ZhangCardiovascular Medicine, Tianshui First People's Hospital, Tianshui City, Gansu Province, 741000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate the influencing factors for acute myocardial infarction (AMI) complicated by cardiac rupture (CR),evaluate the predictive value of the systemic inflammation response index (SIRI), and construct a clinically practical risk prediction model. Methods: A total of 53 AMI patients complicated with CR admitted to Tianshui First People's Hospital from January 2013 to December 2023 were enrolled as the CR group.During the same period, 159 AMI patients without CR were selected as the control group at a 1:3 ratio, matched for age and sex.Baseline data, clinical indicators, and laboratory test results of patients in both groups were collected, and SIRI was calculated. Lasso regression was used to screen core variables, multivariate Logistic regression analysis was performed to identify independent influencing factors, a nomogram prediction model was constructed based on key variables, and the receiver operating characteristic (ROC) curve was used to evaluate the model's efficacy. Results: Multivariate Logistic regression analysis showed that admission heart rate (OR = 1.050,95% CI = 1.024-1.075, P < 0.001), Killip classification (OR = 2.092,95% CI = 1.460-2.997, P < 0.001) and SIRI (OR = 1.105,95% CI = 1.022-1.196, P = 0.012) were independent risk factors for CR in AMI patients. Primary PCI (OR = 0.239,95% CI = 0.097-0.589, P = 0.002) and taking ACEI / ARB drugs within 24 hours (OR = 0.173,95% CI = 0.060-0.500, P = 0.001) were protective factors. The ROC curve model constructed based on the above five indicators has an area under the curve (AUC) of 0.885. Conclusion: Admission heart rate, Killip classification, and systemic inflammatory response index are independent risk factors for AMI with CR. Primary PCI and the administration of ACEI/ARB within 24 hours of admission were identified as protective factors against CR. The nomogram model demonstrated good predictive value for the occurrence of cardiac rupture in patients with AMI.

Indexed as

acute myocardial infarctioncardiac rupturenomogrampredictive factorssystemic inflammation response index

Identifiers

PMID42057923
PMCPMC13123552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.