ArticleLaryngoscope investigative otolaryngology2026
Outcomes of Head and Neck Free Flap Reconstruction Among Patients With Alcohol Use Disorder.
Article in Laryngoscope investigative otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Efficacy of Aspirin Usage in Free Flap Reconstruction of the Head and Neck.Laryngoscope investigative otolaryngology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To compare head and neck free flap outcomes and complications among patients with a history of alcohol use disorder. Methods: This is a multicenter retrospective study from January 1, 2010 to July 31, 2025 using data from 73 healthcare organizations in the United States. Adult patients 18 years or older with head and neck cancer undergoing non-bony or bony free flap reconstruction were divided based on presence or absence of a history of alcohol use disorder before surgery. Primary outcomes examined up to 30 days after surgery included flap failure, need for vascular repair, and flap revision. Results: Patients with a history of alcohol use disorder within 6 months of surgery who underwent bony reconstruction had an increased risk of needing flap revision surgery and pneumonia (RR: 1.293[1.018, 1.642]; 1.947[1.337, 2.836]). A history of alcohol use disorder within 1 year prior to non-bony free flap surgery had a higher risk of flap revision. (RR: 1.218[1.008, 1.472]). Sepsis and pneumonia were noted to have increased risks in relation to alcohol use disorders (RR: 1.522[1.055, 2.196]; 2.011[1.568, 2.581]). The risk of flap failure was not associated with a history of alcohol use disorders (RR: 1.159[0.878, 1.531]). Conclusion: Alcohol use disorder within 6 months prior to surgery is associated with an increased risk of flap revision surgery for bony reconstruction cases. For both non-bony and bony free flaps, the risks of sepsis and pneumonia also increase significantly with alcohol use disorder. Level of Evidence: Level 3.
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