Evidence map›Paper›PMID 42057841›Full record

ArticleWorld journal of radiology2026

Magnetic resonance imaging as a non-invasive breast cancer tool - the relevance of breast edema score: A retrospective study.

Anna Vasilska, Silvia Tsvetkova, Katya Doykova, Lyubomir Chervenkov, Tsvetelina Velikova, Margarita Vasilska, Sara Sariyan

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Article in World journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Anna VasilskaDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Silvia TsvetkovaDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Katya DoykovaDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Lyubomir ChervenkovDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Tsvetelina VelikovaMedical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria.
Margarita VasilskaDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.
Sara SariyanDepartment of Diagnostic Imaging, Medical University of Plovdiv, Plovdiv 4000, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast magnetic resonance imaging (MRI) provides valuable information for tumor detection, as well as potential applications in molecular characterization and prognostication. A key feature detectable on MRI is the presence of breast edema, which has been associated with tumor aggressiveness and poorer clinical outcomes.

aimTo determine the correlation between intramammary edema patterns as observed on breast MRI and the histopathological and molecular characteristics of the tumor.

methodsIn this retrospective single-center study, 123 women with biopsy-proven breast cancer underwent preoperative breast MRI from June 2022 to June 2025. The classification of edema was determined on T2-weighted images, divided into four breast edema score (BES) categories: BES-1 (no edema), BES-2 (peritumoral edema), BES-3 (prepectoral edema), and BES-4 (subcutaneous edema). The MRI findings were correlated with histological type, molecular subtype, receptor status, Ki67 index, and lymph node involvement. Data analysis was conducted using IBM SPSS Statistics for Windows, version 28.

resultsEdema was observed in 45.5% of patients. Statistically significant correlation was observed between BES and molecular subtypes (

conclusionThe presence and severity of MRI-based breast edema score have been found to correlate with aggressive molecular subtypes, underscoring the potential role of BES in prognostic stratification and guiding tailored treatment strategies.

Indexed as

Breast cancerBreast edema scoreBreast magnetic resonance imagingHormone receptor statusHuman epidermal growth factor receptor 2 expressionIntramammary edemaKi-67 proliferation indexMolecular subtypePrognostic imaging biomarkerT2-weighted imaging

Identifiers

PMID42057841
PMCPMC13122042

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