Evidence map›Paper›PMID 42057809›Full record

ArticleOpen forum infectious diseases2026

A Prospective Incidence Study on Sexually Transmitted Infections and HIV in Men Who Have Sex With Men, With or Without Use of Pre-exposure Prophylaxis.

Klaus Jansen, Trevor A Crowell, Patrick F Ottensmeyer, Allahna L Esber, Gyde Steffen, Heiko K Jessen, Christiane Cordes, Stefan Scholten, Stephan Schneeweiss, Norbert H Brockmeyer and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Klaus JansenDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.ORCID https://orcid.org/0000-0002-4878-9421
Trevor A CrowellU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.ORCID https://orcid.org/0000-0001-5947-265X
Patrick F OttensmeyerInstitute of Virology, Medical Faculty, University Bonn, Bonn, Germany.
Allahna L EsberU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.ORCID https://orcid.org/0000-0001-5337-0126
Gyde SteffenDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Heiko K JessenPrivate practice, Jessen+Jessen, Berlin, Germany.
Christiane CordesInfektionsmedizin Berlin-Friedrichshain, Berlin, Germany.ORCID https://orcid.org/0009-0001-1926-2081
Stefan ScholtenPrivate practice, Hohenstaufenring, Cologne, Germany.
Stephan SchneeweissPrivate practice, Hohenstaufenring, Cologne, Germany.
Norbert H BrockmeyerWIR-Walk in Ruhr, Center for Sexual Health and Medicine, Bochum, Germany.
Christoph D SpinnerTUM School of Medicine and Health, Department of Clinical Medicine-Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0002-3875-5367
Markus BickelInfektiologikum Frankfurt, Frankfurt, Germany.
Stefan EsserInstitute for the Research on HIV and AIDS-Associated Diseases Essen, University Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-3625-9650
Axel Baumgartenzfi- Zentrum für Infektiologie Berlin Prenzlauer Berg GmbH, Berlin, Germany.
Albrecht StoehrInstitute for Interdisciplinary Medicine, Hamburg, Germany.
Clara LehmannDepartment I for Internal Medicine, Faculty of Medicine at University Hospital Cologne, Cologne, Germany.
Jörg J VehreschildGerman Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Bonn, Germany.
Tsedal MebrahtuU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Julie Dorsey-SpitzU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Alexandra KnorrInstitute for the Research on HIV and AIDS-Associated Diseases Essen, University Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0009-0008-3884-7617
Anna-Lena BrillenInstitute for the Research on HIV and AIDS-Associated Diseases Essen, University Duisburg-Essen, Essen, Germany.
Jernej PusnikInstitute of Virology, Medical Faculty, University Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0002-5987-8606
Carsten TiemannLaboratory Krone, Bad Salzuflen, Germany.ORCID https://orcid.org/0000-0003-0240-1468
Nelson L MichaelWalter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Merlin L RobbU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Hendrik StreeckInstitute of Virology, Medical Faculty, University Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While pre-exposure prophylaxis (PrEP) can prevent HIV acquisition, associated behavioral changes may increase risk of acquiring other sexually transmitted infections (STIs). Methods: The prospective multicenter BRAHMS study enrolled men who were HIV negative, had sex with men, and were aged 18 to 55 years and reported an increased risk to acquire STI. At 3-month intervals for up to 12 months, participants answered questionnaires and underwent site-specific screening for Results: The mean age of 1017 participants was 33 years, 54.7% used PrEP at enrollment, and 83.7% reported PrEP use overall. Any STI was diagnosed in 71.8% (CT, 40.4%; MG, 38.5%; NG, 36.0%; syphilis, 10.1%; HIV, 0.5%). PrEP users exhibited a higher prevalence for anorectal infections with CT (35.3% vs 20.5%, Conclusions: PrEP use was associated with increased STI risk in our cohort. CT and NG incidence decreased in a structured test-and-treat setting.

Identifiers

PMID42057809
PMCPMC13123855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.