Evidence map›Paper›PMID 42057659›Full record

ArticleThoracic cancer2026

Extended Indications for Sleeve Lobectomy: A Single-Center Experience of Surgical Management of Central Pulmonary Metastases.

V Verzeletti, A Busetto, A Bonis, F Shamshoum, G Pagliarini, M Mammana, E Faccioli, A Rebusso, G Cannone, G M Comacchio and 2 more

Abstract read
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In one paragraph

Article in Thoracic cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

V VerzelettiDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.ORCID https://orcid.org/0000-0001-7239-1248
A BusettoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
A BonisDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
F ShamshoumDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
G PagliariniDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
M MammanaThoracic Surgery Unit and Lung Transplant Centre, Division of Surgery, University -Hospital of Padua, Padua, Italy.ORCID https://orcid.org/0000-0003-0885-2403
E FaccioliDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
A RebussoThoracic Surgery Unit and Lung Transplant Centre, Division of Surgery, University -Hospital of Padua, Padua, Italy.
G CannoneThoracic Surgery Unit and Lung Transplant Centre, Division of Surgery, University -Hospital of Padua, Padua, Italy.
G M ComacchioDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
M SchiavonDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.
A Dell' AmoreDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy.ORCID https://orcid.org/0000-0002-1384-7441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of bronchial sleeve resection for centrally located pulmonary metastases remains poorly defined, as surgery in metastatic disease is often perceived as excessively aggressive. However, in selected patients, this parenchyma-sparing technique may offer durable local control and significant symptomatic relief. This study reports a single-center experience with sleeve resections performed for metastatic, centrally located pulmonary lesions.

methodsAll consecutive patients undergoing bronchial sleeve resection for metastatic disease at Padua University Hospital between January 2000 and August 2025 were retrospectively reviewed. Clinical characteristics, operative details, perioperative outcomes, and follow-up data were collected. Patients treated with sleeve resections for primary lung cancer were excluded.

resultsEighteen patients were included. Most had good performance status, and 66% received preoperative systemic therapy. Single sleeve resections were performed in 72% and double sleeves in 28%. Surgical access was thoracotomy in 72% and VATS in 28%. No in-hospital, 30-day, or 90-day mortality occurred. Postoperative symptom resolution was achieved in 94% of patients. The most frequent histology was colorectal adenocarcinoma. Median follow-up was 26 months, with a median disease-free survival of 22 months. Local recurrence occurred in only one case, and no bronchial stump recurrences were observed.

conclusionBronchial sleeve resection for centrally located pulmonary metastases can be feasible and safe in a carefully selected subset of patients. It provides effective restoration of airway patency, good local control, and acceptable long-term outcomes. Larger multicenter studies are needed to further clarify its role within multidisciplinary management.

Indexed as

Lung NeoplasmsPneumonectomyAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studiescentral pulmonary metastasislung metastasisquality of lifesleeve lobectomysurgery

Identifiers

PMID42057659
PMCPMC13129486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.