SynthesisEpidemiology and infection2026
A comparison of frequentist and Bayesian methods for meta-analysis of diagnostic test accuracy studies.
Synthesis in Epidemiology and infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Diagnostic test accuracy studies assess a diagnostic test's performance against a reference standard. In this review, we explore and compare statistical methods used in meta-analyses of diagnostic test accuracy studies. Specifically, we evaluate two frequentist methods - split component synthesis (SCS) and bivariate model (BM) - alongside two Bayesian approaches: Bayesian hierarchical summary receiver operating characteristic (BHSROC) and Bayesian bivariate model (BBM). We also include their latent class variants (LC-BHSROC and LC-BBM). Using a meta-analysis of various multiplex nucleic acid amplification tests (NAATs/PCRs) against
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