Evidence map›Paper›PMID 42057217›Full record

ArticleTropical medicine and health2026

COVID-19 vaccine booster uptake among healthcare workers in Bangladesh: predictors, challenges, and lessons from a low-income setting.

Md Zakiul Hassan, Ahamed Khairul Basher, Homayra Rahman Shoshi, Md Abdullah Al Jubayer Biswas, Ashrak Shad Pyash, Saleh Haider, Md Azazul Haque, Aninda Rahman, Md Nazmul Islam, Fahmida Chowdhury and 3 more

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Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Md Zakiul HassanProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh. zhassan@icddrb.org.
Ahamed Khairul BasherProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Homayra Rahman ShoshiProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Md Abdullah Al Jubayer BiswasProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Ashrak Shad PyashProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Saleh HaiderProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Md Azazul HaqueProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Aninda RahmanCommunicable Disease Control, The Director General of Health Services, The Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh.
Md Nazmul IslamCommunicable Disease Control, The Director General of Health Services, The Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh.
Fahmida ChowdhuryProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Taufiqur Rahman BhuiyanProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Mohammed Ziaur RahmanProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.
Firdausi QadriProgramme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (Icddr,B), Mohakhali, Dhaka, Bangladesh.

Funding

The U.S. Centre for Disease Control and Prevention (CDC) GR-02312
6 · The paper itself

Abstract

backgroundHealthcare workers (HCWs) remain at an elevated risk of SARS-CoV-2 infection due to occupational exposure and waning vaccine-induced immunity. We conducted a longitudinal study to estimate cumulative uptake, incidence, and factors associated with COVID-19 booster dose uptake among Bangladeshi HCWs.

methodsBetween March 2021 and December 2023, we followed 3099 HCWs recruited from 20 healthcare facilities across four divisions of Bangladesh. At enrollment, information was collected on sociodemographic and clinical characteristics, prior SARS-CoV-2 infection, and COVID-19 vaccination history. Booster uptake status was updated biweekly. Multivariable Cox proportional hazards regression models were used to estimate adjusted hazard ratios (aHRs) for predictors of booster uptake.

resultsDuring follow-up, 1964 (63.4%) HCWs received at least one COVID-19 booster dose. However, uptake of the 2nd booster dose was low (6%). The incidence of booster uptake was 54.5 per 100 person-years (95% CI 50.0-59.5). The hazard of booster uptake was higher among HCWs with prior SARS-CoV-2 infection (aHR = 1.13; 95% CI 1.01-1.26) and among those working in both COVID-19 and general wards (aHR = 1.36; 95% CI 1.22-1.53). In contrast, prior adverse events following the primary series (aHR = 0.36; 95% CI 0.32-0.41) were associated with a lower hazard of booster uptake.

conclusionsAlthough more than half of HCWs received a booster, uptake declined with repeated dosing. Variations in the hazard of uptake by occupational exposure, prior infection, and adverse events reflect changing perceptions of risk and experiential factors in addition to access. Strengthening institutional vaccination policies and addressing behavioral barriers may thus support timely booster uptake among HCWs.

Indexed as

BangladeshBooster uptakeCOVID-19 vaccineHealthcare workers

Identifiers

PMID42057217
PMCPMC13188425

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.