Evidence map›Paper›PMID 42056508›Full record

ArticleNature2026

Evolutionary characterization of lung cancer metastasis.

Sonya Hessey, Abigail Bunkum, Ariana Huebner, Kerstin Haase, Kristiana Grigoriadis, Cristina Naceur-Lombardelli, Wing Kin Liu, Caitlin F Harrigan, Charlotte Grieco, Daniele Marinelli and 56 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. [Evolution of metastases in non-small-cell lung cancer: preliminary results from the TRACERx-PEACE study].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors.

Sonya Hessey *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Abigail Bunkum *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-7753-9421
Ariana Huebner *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0001-8009-4999
Kerstin Haase *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Kristiana Grigoriadis *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Cristina Naceur-Lombardelli *Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-7097-0307
Wing Kin LiuCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Caitlin F HarriganDepartment of Computer Science, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-9243-9648
Charlotte GriecoCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Daniele MarinelliCancer Metastasis Laboratory, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-6002-363X
Boyue DingDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Carlos Martínez-RuizCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-4817-0565
Piotr PawlikCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Mark S HillCancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, UK.
Olivia LucasCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0001-8169-7767
Corentin RichardCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Oriol PichCancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0002-1956-1882
Kerstin TholCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-4624-118X
Takahiro KarasakiCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0001-6863-2360
Sophia WardCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-6777-5279
Foteini AthanasopoulouCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Monica SivakumarCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Selvaraju VeeriahCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Antonia TonchevaCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Andrew J RowanCancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, UK.
Paulina PrymasCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Hayley BridgerCancer Research UK and UCL Cancer Trials Centre, London, UK.
Miriam MitchisonDepartment of Cellular Pathology, University College London Hospitals, London, UK.
Elaine BorgDepartment of Cellular Pathology, University College London Hospitals, London, UK.
Mary FalzonDepartment of Cellular Pathology, University College London Hospitals, London, UK.
Ian ProctorDepartment of Cellular Pathology, University College London Hospitals, London, UK.
Ula MahadevaDepartment of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Anna GreenDepartment of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Martin D ForsterCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Sarah BenafifDepartment of Oncology, University College London Hospitals, London, UK.
Tanya AhmadDepartment of Oncology, University College London Hospitals, London, UK.
Siow Ming LeeCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Dionysis Papadatos-PastosDepartment of Oncology, University College London Hospitals, London, UK.
Babu NaiduBirmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
Gerald LangmanUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Matthew G KrebsDivision of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Pedro OliveiraDepartment of Pathology, The Christie NHS Foundation Trust, Manchester, UK.
Fiona H BlackhallDivision of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Yvonne SummersDivision of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Jamie WeaverDivision of Cancer Sciences, University of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
John Le QuesneCancer Research UK Scotland Institute, Glasgow, UK.ORCID http://orcid.org/0000-0003-3552-7446
Anne ThomasLeicester Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Cathy RichardsDepartment of Histopathology, University Hospitals of Leicester NHS Trust, Leicester, UK.
Dean A FennellUniversity of Leicester, Leicester, UK.
Sanjay JogaiUniversity Hospital Southampton NHS Trust, Southampton, UK.
Judith CaveDepartment of Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Patricia RoxburghSchool of Cancer Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0001-9869-591X
Sioban FraserCancer Research UK Scotland Institute, Glasgow, UK.
Alan KirkGolden Jubilee National Hospital, Clydebank, UK.ORCID http://orcid.org/0000-0001-7317-523X
Kevin G BlythCancer Research UK Scotland Institute, Glasgow, UK.
Peter RussellPrincess Alexandra Hospital, Princess Alexandra Hospital NHS Trust, Harlow, UK.
Crispin T HileyCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.
Allan HackshawCancer Research UK and UCL Cancer Trials Centre, London, UK.ORCID http://orcid.org/0000-0002-5570-5070
TRACERx Consortium
TRACERx EVO Consortium
PEACE consortium
David A MooreCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.ORCID http://orcid.org/0000-0002-6296-1312
Simone ZaccariaCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. s.zaccaria@ucl.ac.uk.ORCID http://orcid.org/0000-0002-5265-7392
Nicholas McGranahanCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. nicholas.mcgranahan.10@ucl.ac.uk.ORCID http://orcid.org/0000-0001-9537-4045
Charles SwantonCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. charles.swanton@crick.ac.uk.ORCID http://orcid.org/0000-0002-4299-3018
Mariam Jamal-HanjaniCancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. m.jamal-hanjani@ucl.ac.uk.ORCID http://orcid.org/0000-0003-1212-1259

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited understanding of the biological processes that govern metastatic dissemination hinders its prevention and treatment

Indexed as

Carcinoma, Non-Small-Cell LungEvolution, MolecularLung NeoplasmsNeoplasm MetastasisAgedClone CellsDNA Copy Number VariationsFemaleHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID42056508
PMCPMC13190308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.