Evidence map›Paper›PMID 42056506›Full record

ArticleNature2026

Pervasive and programmed nucleosome distortion on single chromatin fibres.

Marty G Yang, Hannah J Richter, Simai Wang, Colin P McNally, Camille M Moore, Ali Emadi, Nicole E Harris, Simaron Dhillon, Michela Maresca, Huimin Pan and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Marty G Yang *Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.
Hannah J Richter *Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8954-9136
Simai Wang *Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0009-0005-2292-6116
Colin P McNallyGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.
Camille M MooreGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-3324-789X
Ali EmadiArc Institute, Palo Alto, CA, USA.ORCID http://orcid.org/0000-0002-2224-8854
Nicole E HarrisGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0009-0000-1713-5559
Simaron DhillonLiver Center, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0009-0000-5820-2869
Michela MarescaDivision of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Huimin PanDivision of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-1213-9136
Hayden SaundersDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-7582-3031
Ruiqiao YangSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-5758-9851
Megan S OstrowskiGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-9845-9319
Erika C AndersonCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-0029-6230
Elzo de WitDivision of Gene Regulation, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2883-1415
Jacquelyn J MaherLiver Center, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2509-8484
Yuhong FanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-4431-6990
Geeta J NarlikarDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-1920-0147
Elphège P NoraDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-8347-4396
Holger WillenbringLiver Center, University of California, San Francisco, San Francisco, CA, USA.
Hani GoodarziDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA. hani.goodarzi@ucsf.edu.ORCID http://orcid.org/0000-0002-9648-8949
Vijay RamaniGladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA. vijay.ramani@gladstone.ucsf.edu.ORCID http://orcid.org/0000-0003-3345-5960

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
NRSA Hepatology Training GrantT32DK060414 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mandana Khalili, JACQUELYN J. MAHER · 2002 to 2026
$6.8M
NIDDK NIH HHS P30 DK026743NIDDK NIH HHS T32 DK060414
6 · The paper itself

Abstract

Despite decades of biochemical and structural studies of the nucleosome

Indexed as

ChromatinNucleosomesAnimalsChromatin Assembly and DisassemblyDNADNA FootprintingHepatocyte Nuclear Factor 3-betaHistonesHumansMiceMouse Embryonic Stem CellsPromoter Regions, GeneticTranscription FactorsChromatinDNAFoxa2 protein, mouseHepatocyte Nuclear Factor 3-betaHistonesNucleosomesTranscription Factors

Identifiers

PMID42056506
PMCPMC13253354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.