Evidence map›Paper›PMID 42056354›Full record

ArticlePituitary2026

Decision-making and impulsivity in cabergoline-treated prolactinoma: findings from Iowa Gambling, Go/No-Go, and barratt scales.

Püren Gökbulut, Hüseyin Nergiz, Hatice Ceren Tırış, Işılay Taşkaldıran, Volkan Gökbulut, Şerife Mehlika Kuşkonmaz

Abstract read
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In one paragraph

Article in Pituitary, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Püren GökbulutDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey. puren_gokbulut@hotmail.com.ORCID http://orcid.org/0000-0002-6287-7655
Hüseyin NergizDepartment of Psychology, Faculty of Letters, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-3134-6322
Hatice Ceren TırışDepartment of Psychology, Faculty of Letters, Hacettepe University, Ankara, Turkey.
Işılay TaşkaldıranDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-1390-7571
Volkan GökbulutDepartment of Gastroenterology, Ankara City Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-7906-2479
Şerife Mehlika KuşkonmazDepartment of Endocrinology and Metabolic Diseases, Ankara Training and Research Hospital, Ankara, Turkey.ORCID http://orcid.org/0000-0002-2602-1657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess impulsivity, decision-making performance and inhibitory control in prolactinoma patients treated with dopamine agonists (DA), and to compare these parameters with healthy control(HC) subjects.

methodsA total of 34 patients with prolactinoma, and 35 HCs were included in the study. All patients and controls were screened using demographic information questionnaire, Barratt Impulsiveness Scale–Short Form (BIS-11-SF), Iowa Gambling Task and Go/No-Go Task. Clinical data of all subjects were collected from their electronic medical records.

resultsCompared with healthy controls, patients with prolactinoma receiving dopamine agonist therapy showed a significantly higher frequency of gambling urges and sexual desire during the preceding four weeks (p = 0.003 for both). In the Go/No-Go Task, a significant between-group difference was observed in commission error rates (p = 0.041). Treatment duration was positively correlated with both the frequency of sexual desire over the past four weeks and the non-planning subscale of the BIS-11-SF (r = 0.364, p = 0.035; r = 0.429, p = 0.011, respectively). Cumulative dopamine agonist dose was positively correlated with the frequency of sexual desire, the frequency of sexual intercourse attempts over the past four weeks, and the non-planning subscale of the BIS-11-SF (r = 0.405, p = 0.018; r = 0.433, p = 0.011; and r = 0.418, p = 0.014, respectively).

conclusionsIn patients with prolactinoma, dopamine agonist treatment is associated with selective alterations in decision-making–related impulsivity and inhibitory control, influenced by treatment duration and cumulative dopamine agonist exposure.

Indexed as

CabergolineDecision MakingDopamine AgonistsImpulsive BehaviorPituitary NeoplasmsProlactinomaAdultFemaleGamblingHumansMaleMiddle AgedCabergolineDopamine AgonistsCabergolineDopamine agonistImpulsivityProlactinomaSide effect

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.