Evidence map›Paper›PMID 42056352›Full record

ArticleScientific reports2026

The effect of human ratings reliability on machine learning model performance: a case study in infant pain assessment.

Edoardo Passarotto, Daniel Müllensiefen, Ivan Tomasi, Valentina Brino, Matilde Paramento, Emanuela Formaggio, Stefano Masiero, Maria Rubega

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Edoardo PassarottoDepartment of Neuroscience, University of Padova, Padova, Italy. edoardo.passarotto@unipd.it.
Daniel MüllensiefenInstitute of Systematic Musicology, University of Hamburg, Hamburg, Germany.
Ivan TomasiL'Inglesina Baby Spa, Altavilla Vicentina, Vicenza, Italy.
Valentina BrinoDepartment of Neuroscience, University of Padova, Padova, Italy.
Matilde ParamentoDepartment of Neuroscience, University of Padova, Padova, Italy.
Emanuela FormaggioDepartment of Neuroscience, University of Padova, Padova, Italy.
Stefano MasieroDepartment of Neuroscience, University of Padova, Padova, Italy.
Maria RubegaDepartment of Neuroscience, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human-annotated data is foundational for supervised machine learning (ML). Low inter-rater reliability often introduces noise that degrades model performance. This study investigates how human rating reliability and panel size impact ML efficacy, and introduces a novel debiasing procedure utilizing Random Effects Models (REMs) to mitigate annotator noise. We conducted two complementary experiments to evaluate these dynamics. Experiment 1 analyzed real-world assessments from nine evaluators classifying 355 infant images. Results demonstrated that panel size and specific psychometric reliability indices-namely Cronbach's α, Generalizability, and Dependability coefficients-are strong predictors of ML performance across four algorithms, whereas inter-class correlation coefficients proved less robust. Experiment 2 generated simulated datasets mimicking Experiment 1 - incorporating 40 virtual raters with varying expertise levels and structured pattern noise - to evaluate the robustness of model aggregation across diverse rating scenarios. These simulations confirmed that while annotator noise significantly impairs classification, the proposed REM-based debiasing procedure effectively recovers ground-truth scores. Notably, ML models trained on REM-debiased data from merely two raters achieved predictive performance comparable to models utilizing mean-aggregated scores from eight raters. Ultimately, this study underscores the critical importance of psychometrically sound data curation, demonstrating that advanced debiasing techniques can substantially enhance ML accuracy and efficiency even with small expert panels.

Indexed as

Machine LearningPain MeasurementAlgorithmsClassification AlgorithmsHumansInfantPredictive Learning ModelsReproducibility of ResultsDebiasHuman judgmentsMachine learningRatingsReliability

Identifiers

PMID42056352
PMCPMC13320211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.