Evidence map›Paper›PMID 42056329›Full record

Trial reportScientific reports2026

Physiological and psychological effects of Wagyu beef taste stimulation: a randomized crossover trial.

Harumi Ikei, Hyunju Jo, Hideki Hirano, Yoshifumi Miyazaki

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Harumi Ikei *Institute for Advanced Academic Research, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan. hikei@chiba-u.jp.ORCID http://orcid.org/0000-0001-5126-9198
Hyunju JoCenter for Environment, Health and Field Sciences, Chiba University, 6-2-1 Kashiwa-no-ha, Kashiwa, Chiba, 277-0882, Japan.
Hideki HiranoHimeji University, 2042-2 Oshio-cho, Himeji, Hyogo, Japan.
Yoshifumi Miyazaki *Center for Environment, Health and Field Sciences, Chiba University, 6-2-1 Kashiwa-no-ha, Kashiwa, Chiba, 277-0882, Japan. ymiyazaki@faculty.chiba-u.jp.ORCID http://orcid.org/0000-0002-3170-6810

Funding

Himeji City Industry-Academia Collaborative Research Grant None
6 · The paper itself

Abstract

The effects of Japanese Wagyu beef consumption have primarily relied on subjective assessments, with limited investigation into physiological indicators. This study aimed to evaluate psychological and physiological responses to taste stimulation with Wagyu beef in a controlled setting. Forty-nine healthy university students participated. Psychological responses were assessed using a modified semantic differential method and the Profile of Mood States, Second Edition. Physiological responses were measured using heart rate variability to evaluate autonomic nervous activity and near-infrared time-resolved spectroscopy to assess prefrontal cortex oxyhemoglobin concentrations. The experimental stimulus comprised 4 g of Wagyu beef, whereas an equal amount of soy-based alternative meat was used as a control. Compared with the control, taste stimulation with Wagyu beef substantially enhanced subjective feelings of comfort and relaxation and improved mood states. Although no direct differences were observed in autonomic nervous activity or prefrontal cortex activity between conditions, correlation analyses revealed that higher subjective ratings of deliciousness were associated with increased parasympathetic activity during rest and reduced sympathetic activity under stress. In conclusion, these findings demonstrate that perceived deliciousness evoked by Wagyu beef is correlated with physiological relaxation, as reflected in modulation of autonomic nervous system activity.Trial registration: University Hospital Medical Information Network Clinical Trials Registry (UMINCTR), UMIN000048826 (registered on 2 September 2022) and UMIN000046575 (registered on 7 January 2022).

Indexed as

Red MeatTasteAdultAffectAnimalsAutonomic Nervous SystemCattleCross-Over StudiesFemaleHeart RateHumansMalePrefrontal CortexYoung AdultAutonomic nervous activityHeart rate variabilityPhysiological–psychological interactionsSemantic differential methodTaste stimulationWagyu beef

Identifiers

PMID42056329
PMCPMC13324031

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.