Evidence map›Paper›PMID 42056263›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

High- and low-frequency accelerated repetitive transcranial magnetic stimulation for major depressive disorder.

Chaeyeon Yang, Yun Ji Kim, Jihye Ahn, Sehyun Jeon, Jooyoung Lee, Su-Young Song, Seog Ju Kim

Abstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chaeyeon YangDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Yun Ji KimDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Jihye AhnDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Sehyun JeonDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Jooyoung LeeDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Su-Young SongDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Seog Ju KimDepartment of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea. ksj7126@skku.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study examined the effects of two accelerated repetitive transcranial magnetic stimulation (rTMS) protocols in patients with major depressive disorder (MDD).

methodsTwenty-two patients received accelerated high-frequency rTMS (HF-rTMS; 10 Hz, left prefrontal cortex), and 18 received accelerated low-frequency rTMS (LF-rTMS; 1 Hz, right prefrontal cortex). Each participant underwent 10 sessions over 2 consecutive days (5 sessions per day). Depression, anxiety, and sleep quality were assessed using the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and Pittsburgh Sleep Quality Index (PSQI), respectively. Clinical outcomes were evaluated at baseline and at 1 day, 2 weeks, and 4 weeks after treatment.

resultsHAM-D scores significantly decreased from baseline after accelerated rTMS and remained improved over 4 weeks. Both HF-rTMS and LF-rTMS produced comparable early reductions in depression severity, with LF-rTMS showing a greater HAM-D reduction at 4 weeks. HAM-A and PSQI scores also improved at 2 and 4 weeks in both groups, with no significant between-group differences.

conclusionsBoth accelerated HF- and LF-rTMS protocols were associated with improvements in depressive, anxiety and sleep symptoms in patients with MDD, and LF-rTMS may confer more sustained antidepressant effects.

Indexed as

Major Depressive DisorderPrefrontal CortexTranscranial Magnetic StimulationAdultAnxietyFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesTreatment OutcomeAccelerated repetitive transcranial magnetic stimulationAnxietyDepressionSleepTreatment

Identifiers

PMID42056263
PMCPMC13481570

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.