Evidence map›Paper›PMID 42056155›Full record

ArticleScientific reports2026

The impact of collimator angle and increment on volumetric modulated arc therapy after modified radical mastectomy for breast cancer.

Haiyang Wang, Yifei Pi, Chunbo Liu, Xiaoxiao Zuo, Xin Wang, Bin Han, Xi Pei, Ran Lv, Xie George Xu, Chengzhang Long and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Haiyang WangDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yifei PiDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chunbo LiuDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaoxiao ZuoDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xin WangDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Bin HanDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xi PeiInstitute of Nuclear Medical Physics, University of Science and Technology of China, Hefei, China.
Ran LvDepartment of Radiation Oncology, The second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Xie George XuInstitute of Nuclear Medical Physics, University of Science and Technology of China, Hefei, China.
Chengzhang LongMedical and Ionizing Radiation Metrology Testing Research Center, Henan Provincial Institute of Metrology and Testing Sciences, Zhengzhou, China.
Yuexin GuoDepartment of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Panfeng WangMedical and Ionizing Radiation Metrology Testing Research Center, Henan Provincial Institute of Metrology and Testing Sciences, Zhengzhou, China. fccwanghy@zzu.edu.cn.

Funding

Anhui Province Key Research and Development Plan 2023s07020020Funding of University of Science and Technology of China (USTC) XDB39040600Henan Province Medical Education Research Project WJLX2024061Henan Province Medical Science and Technology Research Program Provincial and Ministry Co-constructed Youth Project SBGJ202103073Joint Construction Project of Henan Province Medical Science and Technology Research Program LHGJ20190161Key Scientific Research Projects of Henan Provincial Colleges and Universities 23B320004National Natural Science Foundation of China 12275372USTC Fund for New Medicine - Innovation Team Project YD2140002002USTC Fund for the Development of Medical Physics and Biomedical Engineering Interdisciplinary Subjects YD2140000601
6 · The paper itself

Abstract

To investigate the best combination of parameters by changing the collimator and increment in the volumetric modulated arc therapy after modified radical mastectomy for breast cancer. Ten patients with left breast cancer and ten patients with right breast cancer who underwent modified radical mastectomy were selected in our research cohort. Treatment plans were established utilizing the 3-arc beam configuration spanning 240 degrees. The collimator angle was systematically adjusted in increments of 10 degrees, ranging from - 90 to 90 degrees. Additionally, increment values of 10, 20, 30, and 40 were employed for each corresponding collimator angle. All other planning parameters remained constant across the plans. Finally the impact of different values was analyzed in terms of plan quality and execution efficiency. Regarding the dose distribution within the target and the ipsilateral lung, the optimal collimator angles were observed to range from - 60 to 30 degrees for the left breast and from - 30 to 60 degrees for the right breast. As for the increment value, 10 yielded the optimal outcome, 40 resulted in the least desirable outcome, and 20 and 30 demonstrated a balanced effect between 10 and 40. In terms of execution efficiency and treatment complexity, the impact of the collimator angle on the results exhibits symmetric distribution, and the most favorable collimator angle approaches 0 degrees. Additionally, with a gradual increase in the collimator angle, the execution efficiency diminishes while the complexity correspondingly increases. In the context of treatment planning following modified radical mastectomy for left and right breast cancer, optimal collimator angles fall within the ± 30-degree range, while increment values of 20 and 30 degrees yielded the best overall outcomes, ensuring the attainment of the prescribed dose while accounting for execution efficiency and treatment complexity.

Indexed as

Breast NeoplasmsMastectomy, Modified RadicalRadiotherapy, Intensity-ModulatedFemaleHumansMiddle AgedRadiotherapy DosageRadiotherapy Planning, Computer-AssistedCollimatorIncrementInfluential factorsModified radical mastectomy for breast cancerVolumetric modulated arc therapy

Identifiers

PMID42056155
PMCPMC13320181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.