Evidence map›Paper›PMID 42056119›Full record

ArticleNature communications2026

Escalating transmissibility of severe fever with thrombocytopenia syndrome in a high-endemic region of China.

Bingbing Wang, Na Chu, Hongjie Wei, Yulun Xie, Yanshu Ke, Jiaying Chen, Fang Xie, Lei Gong, Jia Rui, Tianmu Chen

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bingbing Wang *State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Na Chu *Department of Acute Infectious Disease Prevention and Control, Anhui Provincial Center for Disease Control and Prevention, Hefei, China.
Hongjie Wei *State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Yulun Xie *State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Yanshu KeState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Jiaying ChenState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Fang XieState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China.
Lei GongDepartment of Acute Infectious Disease Prevention and Control, Anhui Provincial Center for Disease Control and Prevention, Hefei, China. gong0516@126.com.ORCID http://orcid.org/0000-0001-8430-2329
Jia RuiDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha City, China. ruijia5345@163.com.ORCID http://orcid.org/0009-0006-7687-3790
Tianmu ChenState Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, People's Republic of China. chentianmu@xmu.edu.cn.ORCID http://orcid.org/0000-0003-0710-5086

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82404329
6 · The paper itself

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging public health concern with increasing incidence and geographic spread. Quantitative assessment of its cross-species transmission among humans, ticks, and animal hosts remains limited. Here, we develop and apply a multi-population, multi-route dynamic model using data from 3,883 reported cases in Anhui Province, China, from 2019 to 2023 to quantify transmissibility and characterize spatiotemporal patterns. We estimate an average annual incidence of 1.3 per 100,000 and a case fatality rate of 3.1%. Cases are concentrated from April to September, and the transmission season extends into early spring and late autumn. Farmers and older adults are the main high-risk groups, and transmission risk is highest in central and southern Anhui. Model-based estimates indicate increasing transmissibility, with the basic reproduction number exceeding 1 from 2022 and reaching 1.5 in 2023; the highest prefecture-level estimate is 3.3 in Chuzhou. These findings show sustained expansion of SFTS transmission in a high-endemic region and support earlier, geographically targeted interventions for cross-species transmission control.

Indexed as

Endemic DiseasesSevere Fever with Thrombocytopenia SyndromeAnimalsChinaHumansIncidencePhlebovirusSeasonsTicks

Identifiers

PMID42056119
PMCPMC13338359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.