ArticleThe Journal of international medical research2026
Prediction of recurrence in patients with non-acute atherosclerotic middle cerebral artery occlusion: A longitudinal study using computed tomography perfusion and magnetic resonance imaging.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveThis study aimed to assess the performance of time to maximum concentration (Tmax) using computed tomography perfusion for predicting stroke recurrence in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion.MethodsThis retrospective monocentric study enrolled 138 patients diagnosed with non-acute atherosclerotic middle cerebral artery occlusion. In addition to conventional computed tomography angiography or digital subtraction angiography, all patients underwent head computed tomography perfusion and magnetic resonance imaging 7-14 days after stroke and repeat head magnetic resonance imaging at 3-6 weeks. Volume of time to maximum concentration >4 s was considered the hypoperfusion area. The association between imaging characteristics, new ischemic lesion or lesion size increase on magnetic resonance imaging, and patient prognosis was assessed.ResultsIncreased number/area of infarct lesion was observed in 52/138 (37.7%) patients on diffusion weighted imaging 3-6 weeks after the first stroke. The volume of time to maximum concentration >4 s at baseline was strongly associated with infarct lesion development (odds ratio = 1.22 per 10-mL increase, 95% confidence interval: 1.10-1.34,
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