ArticleJournal of the Korean Association of Oral and Maxillofacial Surgeons2026
Evaluation of titanium-prepared platelet-rich fibrin incorporated with amoxiclav, metronidazole, and neem gel on bone regeneration in Wistar rats: a pilot study.
Article in Journal of the Korean Association of Oral and Maxillofacial Surgeons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Objectives: Titanium platelet-rich fibrin (T-PRF) usage as sustained drug delivery system (SDDS) has been recently started. Hence present study aimed to evaluate hard tissue regenerative efficacy of T-PRF clots incorporated with amoxiclav (AMX)/metronidazole (MET)/neem (NE) gels individually in osseous defects created in Wistar rats. Materials and Methods: In this Results: Inflammatory response was reported in T-PRF+MET Group followed by AMX Group and no inflammatory response was recorded for T-PRF plain with statistical significance ( Conclusion: Research results showed that T-PRF can be a SDDS and addition of antibiotics or herbal extract didn't alter the hard tissue healing property of T-PRF and resulted in new bone formation.
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