Evidence map›Paper›PMID 42055630›Full record

ArticleCancer genomics & proteomics

Effects of Isthmus Topography on the Molecular Characteristics of

Chi-Yu Kuo, Sheena Yi-Hsin Cheng, Yi-Chiung Hsu, Shih-Ping Cheng

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Article in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chi-Yu KuoDepartment of Surgery, MacKay Memorial Hospital, Taipei, Taiwan, R.O.C.
Sheena Yi-Hsin ChengUniversity of Southern California, Los Angeles, CA, U.S.A.
Yi-Chiung HsuDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan, R.O.C.
Shih-Ping ChengDepartment of Surgery, MacKay Memorial Hospital, Taipei, Taiwan, R.O.C.; t119@mmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPrevious studies suggest that thyroid cancers in the isthmus are associated with more aggressive behavior and unfavorable patient outcomes compared to lobar tumors. This study aimed to characterize the molecular features of isthmus thyroid cancer. MATERIALS AND

methodsTranscriptomic and proteomic data were retrieved from the Cancer Genome Atlas. We performed 1:2 propensity score matching based on age, sex, tumor subtype, size, extrathyroidal extension, lymph node metastasis, and stage, matching 15 papillary thyroid cancers with the

resultsDespite balanced oncogenic drivers,

conclusion

Indexed as

MutationProto-Oncogene Proteins B-rafThyroid Cancer, PapillaryThyroid NeoplasmsFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedProteomicsBRAF protein, humanProto-Oncogene Proteins B-rafBRAF mutationisthmuspapillary thyroid cancerpropensity score matchingThe Cancer Genome Atlas

Identifiers

PMID42055630
PMCPMC13133813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.